Gold nanoparticles modulate BCG-induced innate immune memory in human monocytes by shifting the memory response towards tolerance

BJ Swartzwelter, F Barbero, A Verde, M Mangini… - Cells, 2020 - mdpi.com
Innate immune memory is characterized by a modulation in the magnitude with which innate
immune cells such as monocytes and macrophages respond to potential dangers …

Trained immunity for personalized cancer immunotherapy: current knowledge and future opportunities

JR Lérias, E De Sousa, G Paraschoudi… - Frontiers in …, 2020 - frontiersin.org
Memory formation, guided by microbial ligands, has been reported for innate immune cells.
Epigenetic imprinting plays an important role herein, involving histone modification after …

[HTML][HTML] Migratory neural crest cells phagocytose dead cells in the developing nervous system

Y Zhu, SC Crowley, AJ Latimer, GM Lewis, R Nash… - Cell, 2019 - cell.com
During neural tube closure and spinal cord development, many cells die in both the central
and peripheral nervous systems (CNS and PNS, respectively). However, myeloid-derived …

Severe SARS‐CoV‐2 patients develop a higher specific T‐cell response

J Demaret, G Lefevre, F Vuotto, J Trauet… - Clinical & …, 2020 - Wiley Online Library
Objectives Assessment of the adaptive immune response against severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) is crucial for studying long‐term immunity and …

Role of Interleukin 1 Receptor 2 in Kidney Disease

H Hu, A Wu, X Mu, H Zhou - Journal of Interferon & Cytokine …, 2024 - liebertpub.com
The interleukin 1 (IL-1) family plays a significant role in the innate immune response. IL-1
receptor 2 (IL-1R2) is the decoy receptor of IL-1. It is a negative regulator that can be …

Methodological approaches to assess innate immunity and innate memory in marine invertebrates and humans

M Auguste, D Melillo, A Corteggio, R Marino… - Frontiers in …, 2022 - frontiersin.org
Assessing the impact of drugs and contaminants on immune responses requires
methodological approaches able to represent real-life conditions and predict long-term …

Surface modification of silver nanoparticle (AgNP) by liposomal encapsulation mitigates AgNP-induced inflammation

A Yusuf, A Casey - Toxicology In Vitro, 2019 - Elsevier
Silver nanoparticles (AgNP) are widely used in a variety of consumable products as
antibacterial to prevent or treat infection. Unfortunately, evidence exits that AgNP induces …

The NLRP3 inflammasome and its role in the pathogenicity of leukemia

L Urwanisch, M Luciano, J Horejs-Hoeck - International journal of …, 2021 - mdpi.com
Chronic inflammation contributes to the development and progression of various tumors.
Especially where the inflammation is mediated by cells of the innate immune system, the …

Development of clobetasol‐loaded biodegradable nanoparticles as an endodontic intracanal medicament

F Elmsmari, JA González Sánchez… - International …, 2024 - Wiley Online Library
Aim The aim of current study is the development and optimization of biodegradable
polymeric nanoparticles (NPs) to be used in the field of Endodontics as intracanal …

Novel Regioisomeric Analogues of Naphthyl-N-Acylhydrazone Derivatives and Their Anti-Inflammatory Effects

D da Costa Salomé, RHCN de Freitas… - International Journal of …, 2022 - mdpi.com
Background: When homeostasis is disturbed it can result in a pathological event named
inflammation. The main drugs used in the treatment consist of non-steroidal and steroidal …