[HTML][HTML] Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm

C Guo, B Li, H Ma, X Wang, P Cai, Q Yu, L Zhu… - Nature …, 2020 - nature.com
Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6)
receptor, including tocilizumab, ameliorate lethal inflammatory responses in COVID-19 …

[HTML][HTML] Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

[HTML][HTML] Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19

R Alon, M Sportiello, S Kozlovski, A Kumar… - Nature Reviews …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …

Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

JR Habel, THO Nguyen… - Proceedings of the …, 2020 - National Acad Sciences
An improved understanding of human T cell-mediated immunity in COVID-19 is important for
optimizing therapeutic and vaccine strategies. Experience with influenza shows that …

Herbal immune-boosters: Substantial warriors of pandemic Covid-19 battle

K Khanna, SK Kohli, R Kaur, A Bhardwaj, V Bhardwaj… - Phytomedicine, 2021 - Elsevier
Current scenario depicts that world has been clenched by COVID-19 pandemic. Inevitably,
public health and safety measures could be undertaken in order to dwindle the infection …

Coronavirus disease 2019 (COVID‐19): An overview of the immunopathology, serological diagnosis and management

AU Anka, MI Tahir, SD Abubakar… - Scandinavian …, 2021 - Wiley Online Library
SARS‐CoV‐2 is a novel human coronavirus responsible for the Coronavirus disease 2019
(COVID‐19) pandemic. Pneumonia and acute respiratory distress syndrome are the major …

[HTML][HTML] Development of point-of-care biosensors for COVID-19

JR Choi - Frontiers in chemistry, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The
deleterious effects of coronavirus have prompted the development of diagnostic tools to …

Uncontrolled innate and impaired adaptive immune responses in patients with COVID-19 acute respiratory distress syndrome

S Hue, A Beldi-Ferchiou, I Bendib… - American journal of …, 2020 - atsjournals.org
Rationale: Uncontrolled inflammatory innate response and impaired adaptive immune
response are associated with clinical severity in patients with coronavirus disease (COVID …

Immunology of COVID‐19: mechanisms, clinical outcome, diagnostics, and perspectives—a report of the European Academy of Allergy and Clinical Immunology …

M Sokolowska, ZM Lukasik, I Agache, CA Akdis… - Allergy, 2020 - Wiley Online Library
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …

Impact of PD-1 blockade on severity of COVID-19 in patients with lung cancers

J Luo, H Rizvi, JV Egger, IR Preeshagul, JD Wolchok… - Cancer discovery, 2020 - AACR
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to dramatic changes
in oncology practice. It is currently unknown whether programmed death 1 (PD-1) blockade …