Modulation of Human Dendritic Cell Functions by Phosphodiesterase-4 Inhibitors: Potential Relevance for the Treatment of Respiratory Diseases

HO Nguyen, L Tiberio, F Facchinetti, G Ripari, V Violi… - Pharmaceutics, 2023 - mdpi.com
Inhibitors of phosphodiesterase-4 (PDE4) are small-molecule drugs that, by increasing the
intracellular levels of cAMP in immune cells, elicit a broad spectrum of anti-inflammatory …

Role of ACE2-Ang (1–7)-Mas axis in post-COVID-19 complications and its dietary modulation

S Sahu, CR Patil, S Kumar, S Apparsundaram… - Molecular and Cellular …, 2022 - Springer
Severe acute respiratory syndrome-coronavirus-2 (COVID-19) virus uses Angiotensin-
Converting Enzyme 2 (ACE2) as a gateway for their entry into the human body. The ACE2 …

[HTML][HTML] Efficacy of umbilical cord mesenchymal stromal cells for COVID-19: A systematic review and meta-analysis

C Yang, R Chen, Q Zhu, S Han, M Kuang - Frontiers in Immunology, 2022 - frontiersin.org
Objectives A major challenge for COVID-19 therapy is dysregulated immune response
associated with the disease. Umbilical cord mesenchymal stromal cells (UC-MSCs) may be …

Asymptomatic COVID-19 individuals tend to establish relatively balanced innate and adaptive immune responses

M Li, Y Zhang, J Lu, L Li, H Gao, C Ma, E Dai, L Wei - Pathogens, 2021 - mdpi.com
The sharp increase in the proportion of asymptomatic cases and the potential risk of virus
transmission have greatly increased the difficulty of controlling the COVID-19 pandemic. The …

Emetine is not ipecac: considerations for its use as treatment for SARS-CoV2

MD Bleasel, GM Peterson - Pharmaceuticals, 2020 - mdpi.com
Emetine is a potent antiviral that acts on many viruses in the low-nM range, with several
studies in animals and humans demonstrating antiviral activity. Historically, emetine was …

Intricate interplay between Covid‐19 and cardiovascular diseases

VC Keri, A Hooda, P Kodan, B RL… - Reviews in Medical …, 2021 - Wiley Online Library
Covid‐19 disease can involve any organ system leading to myriad manifestations and
complications. Cardiovascular manifestations are being increasingly recognised with the …

Radiological Findings as Predictors of COVID-19 Lung Sequelae: A Systematic Review and Meta-Analysis

S Alilou, M Zangiabadian, A Pouramini… - Academic …, 2023 - Elsevier
Background This systematic review and meta-analysis aimed to investigate the radiological
predictors of post-coronavirus disease 19 (COVID-19) pulmonary fibrosis and incomplete …

Ghrelin and leptin concentrations in patients after SARS-CoV2 infection

J Kuliczkowska-Płaksej… - Journal of Clinical …, 2023 - mdpi.com
SARS-CoV2 infection can lead to severe cytokine storm especially in obese patients.
Ghrelin acts not only as an appetite regulator but can also play a key role in the immune …

Autophagy modulation in lymphocytes from COVID-19 patients: new therapeutic target in SARS-COV-2 infection

M Vomero, C Barbati, T Colasanti, AI Celia… - Frontiers in …, 2020 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the novel coronavirus,
causing coronavirus disease 2019 (COVID-19). During virus infection, several pro …

The Association between Admission Procalcitonin Level and The Severity of COVID-19 Pneumonia: A Retrospective Cohort Study

M Aon, A Alsaeedi, A Alzafiri, MM Ibrahim… - Medicina, 2022 - mdpi.com
Background and Objectives: An elevated procalcitonin level has classically been linked to
bacterial infections. Data on the association between elevated procalcitonin and the …