Wet granulation is a key step in the pharmaceutical manufacturing of solid-dosage forms.
Wet granulation is used in pharmaceutical production to enhance formulation qualities such …

Population balance models are tools for the study of dispersed systems, such as granular
materials, polymers, colloids and aerosols. They are applied with increasing frequency …

In this study, a novel mechanistic model for a wet granulation process is presented,
combining the techniques of population balance modeling and discrete element methods to …

In this study, a novel multi-component population balance model (PBM) for the twin-screw
granulation (TSG) process was developed, taking into account the rate processes of …

This study focuses on development of two approaches based on finite volume schemes for
solving both one-dimensional and multidimensional nonlinear simultaneous coagulation …

In pharmaceutical manufacturing, fluidized bed granulation is one of the common
processing options available to achieve better flowability of powders through size …

Three-dimensional (3-D) population balance equations are often used to model wet
granulation processes, simulating distributions in particle size, liquid binder content, and …

In the pharmaceutical industry, twin-screw wet granulation has become a realistic option for
the continuous manufacturing of solid drug products. Towards the efficient design …

In the recent few years, continuous processing has been considered as a promising process
alternative to batch processing in pharmaceutical manufacturing. Via a novel population …

Milling affects not only particle size distributions but also other important granule quality
attributes, such as API content and porosity, which can have a significant impact on the …