[HTML][HTML] Matrix metalloproteinases on severe COVID-19 lung disease pathogenesis: cooperative actions of MMP-8/MMP-2 axis on immune response through HLA-G …

PV da Silva-Neto, VB do Valle, CA Fuzo… - Biomolecules, 2022 - mdpi.com
Patients with COVID-19 predominantly have a respiratory tract infection and acute lung
failure is the most severe complication. While the molecular basis of SARS-CoV-2 …

[HTML][HTML] C-reactive protein: Friend or foe? Phylogeny from heavy metals to modified lipoproteins and SARS-CoV-2

M Torzewski - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Animal C-reactive protein (CRP) has been found in every organism from arthropods to
humans where its presence has been sought implying that these proteins have important …

[HTML][HTML] Association of miR-144 levels in the peripheral blood with COVID-19 severity and mortality

A Madè, S Greco, M Vausort, M Miliotis, E Schordan… - Scientific Reports, 2022 - nature.com
Abstract Coronavirus disease-2019 (COVID-19) can be asymptomatic or lead to a wide
symptom spectrum, including multi-organ damage and death. Here, we explored the …

[HTML][HTML] A review of the effect of COVID-19 on immune responses of the body

Y Hekmatnia, F Rahmani, Z Feili… - Journal of Family …, 2022 - journals.lww.com
After the world faced the epidemic of COVID-19 caused by the novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), novel clinical evidence and …

Soluble HLA-G is upregulated in serum of patients with severe COVID-19

NT Al-Bayatee, AH Ad'hiah - Human Immunology, 2021 - Elsevier
Abstract Soluble HLA-G (sHLA-G) molecules are considered potent immunomodulators, and
their dysregulated expression has been implicated in several pathological conditions …

[HTML][HTML] Induction of pulmonary HLA-G expression by SARS-CoV-2 infection

B Seliger, S Jasinski-Bergner, C Massa… - Cellular and Molecular …, 2022 - Springer
The non-classical human leukocyte antigen (HLA)-G exerts immune-suppressive properties
modulating both NK and T cell responses. While it is physiologically expressed at the …

[HTML][HTML] Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits

SH Kim, J Kim, JY Jang, H Noh, J Park… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus
disease 2019 (COVID-19) has been a global health concern since 2019. The viral spike …

Celastrol: A lead compound that inhibits SARS‐CoV‐2 replication, the activity of viral and human cysteine proteases, and virus‐induced IL‐6 secretion

CA Fuzo, RB Martins, TFC Fraga‐Silva… - Drug Development …, 2022 - Wiley Online Library
The global emergence of coronavirus disease 2019 (COVID‐19) has caused substantial
human casualties. Clinical manifestations of this disease vary from asymptomatic to lethal …

[HTML][HTML] The severity of COVID-19 affects the plasma soluble levels of the immune checkpoint HLA-G molecule

JFC Cordeiro, TM Fernandes, DM Toro… - International Journal of …, 2022 - mdpi.com
The non-classical histocompatibility antigen G (HLA-G) is an immune checkpoint molecule
that has been implicated in viral disorders. We evaluated the plasma soluble HLA-G (sHLA …

[HTML][HTML] Longitudinal trajectories of pneumonia lesions and lymphocyte counts associated with disease severity among convalescent COVID-19 patients: a group …

N Shi, C Huang, Q Zhang, C Shi, F Liu, F Song… - BMC pulmonary …, 2021 - Springer
Background To explore the long-term trajectories considering pneumonia volumes and
lymphocyte counts with individual data in COVID-19. Methods A cohort of 257 convalescent …