Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …

Phosphate is an essential nutrient for life and is a critical component of bone formation, a
major signaling molecule, and structural component of cell walls. Phosphate is also a …

INTRODUCTION Kidney stone disease affects 1 in 10 persons at least once per life-time
worldwide, in 2% the disease is recurrent. For the individual stone disease can be painful …

Na+-dependent phosphate cotransporters NaPi-IIa and NaPi-IIc, located at the brush-border
membrane of renal proximal tubules, are regulated by numerous factors, including fibroblast …

Loss of function mutations in the CYP24A1 gene, involved in vitamin D catabolism and in
calcium homeostasis, are known to be the genetic drivers of both idiopathic infantile …

An overview of the mechanisms in vascular calcification duri... : Current Opinion in Nephrology
and Hypertension An overview of the mechanisms in vascular calcification during chronic kidney …

Objectives: Review the definition of hypophosphatemia. Outline the causes of
hypophosphatemia. Explain the management of hypophosphatemia. Explain how the …

Abstract Aims Dietary inorganic phosphate (Pi) modulates renal Pi reabsorption by
regulating the expression of the NaPi‐IIa and NaPi‐IIc Pi transporters. Here, we aimed to …

Abstract Pulmonary Alveolar Microlithiasis (PAM) is a rare genetic disorder causing
widespread deposition of calcium-phosphate crystals in the alveolar space. A hallmark of …

Tubular effects of sodium–glucose cotransporter 2 inhibitors... : Current Opinion in Nephrology
and Hypertension Tubular effects of sodium–glucose cotransporter 2 inhibitors: intended and …