Long non-coding RNAs in antiviral immunity

T Vierbuchen, KA Fitzgerald - Seminars in Cell & Developmental Biology, 2021 - Elsevier
Tight regulation of the immune response is fundamental for efficient pathogen clearance and
to prevent excessive inflammation. Long non-coding RNAs (lncRNAs) have emerged as …

Cellular Lnc_209997 suppresses Bombyx mori nucleopolyhedrovirus replication by targeting miR‐275‐5p in B. mori

S Lin, SL Zhang, HT Yin, ZM Zhao… - Insect Molecular …, 2022 - Wiley Online Library
Long non‐coding RNA (lncRNA) is a type of non‐coding RNA molecule, which exceeds 200
nucleotides in length and participates in the regulation of a variety of life activities. Recent …

Regulation of signaling mediated by nucleic acid sensors for innate interferon-mediated responses during viral infection

A Takaoka, T Yamada - International immunology, 2019 - academic.oup.com
Type I and type III interferons are important anti-viral cytokines that are massively induced
during viral infection. This dynamic process is regulated by many executors and regulators …

The role of long noncoding RNA BST2-2 in the innate immune response to viral infection

S Chen, X Huang, Q Xie, Q Liu, H Zhu - Journal of virology, 2022 - Am Soc Microbiol
Long noncoding RNAs (lncRNAs) widely exist in the cells and play important roles in various
biological processes. The role of lncRNAs in immunity remains largely unknown. lncRNA …

Interferon response in hepatitis C virus-infected hepatocytes: issues to consider in the era of direct-acting antivirals

PS Sung, EC Shin - International journal of molecular sciences, 2020 - mdpi.com
When interferons (IFNs) bind to their receptors, they upregulate numerous IFN-stimulated
genes (ISGs) with antiviral and immune regulatory activities. Hepatitis C virus (HCV) is a …

Fueling type I interferonopathies: regulation and function of type I interferon antiviral responses

CS Ng, H Kato, T Fujita - Journal of Interferon & Cytokine Research, 2019 - liebertpub.com
In conjunction with the development of genome-wide technology, numerous studies have
revealed the importance of regulatory mechanisms to avoid the onset of autoimmunity. In …

LncRNA LINC02574 inhibits influenza A virus replication by positively regulating the innate immune response

Y Zhang, X Chi, J Hu, S Wang, S Zhao, Y Mao… - International Journal of …, 2023 - mdpi.com
Studies have shown that long noncoding RNAs (lncRNAs) play crucial roles in regulating
virus infection, host immune response, and other biological processes. Although some …

Long noncoding RNAs and the regulation of innate immunity and host-virus interactions

M Basavappa, S Cherry… - Journal of leukocyte …, 2019 - academic.oup.com
Immune responses are both pathogen and cell type-specific. The innate arm of immunity is
characterized by rapid intracellular signaling cascades resulting in the production of …

TRIM10 binds to IFN‐α/β receptor 1 to negatively regulate type I IFN signal transduction

M Guo, W Cao, S Chen, R Tian, L Wang… - European Journal of …, 2021 - Wiley Online Library
The type I interferon (IFN‐I) system is important for antiviral and anticancer immunity.
Prolonged activation of IFN/JAK/STAT signaling is closely associated with autoimmune …

Long non-coding RNAs associated with infection and vaccine-induced immunity

T Lüscher-Dias, IM Conceição, V Schuch… - Essays in …, 2021 - portlandpress.com
The immune system responds to infection or vaccination through a dynamic and complex
process that involves several molecular and cellular factors. Among these factors, long non …