[HTML][HTML] A novel IFNbeta-induced long non-coding RNA ZAP-IT1 interrupts Zika virus replication in A549 cells

Y Huang, Y Su, L Shen, Z Huo, C Chen, T Sun, X Tian… - Virologica Sinica, 2022 - Elsevier
Zika virus (ZIKV) infection can cause severe neurological diseases including neonatal
microcephaly and Guillain-Barre syndrome. Long noncoding RNAs (lncRNAs) are the by …

PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5

R Deng, L Zhang, S Chen, X Li, B Xue, H Li, Y Xu… - Antiviral Research, 2024 - Elsevier
RNA viral infections seriously endanger human health. Src homology 2 (SH2) domain-
containing protein tyrosine phosphatase 2 (SHP2) suppresses innate immunity against …

[HTML][HTML] When does hepatitis B virus meet long-stranded noncoding RNAs?

B Lei, H Song, F Xu, Q Wei, F Wang, G Tan… - Frontiers in …, 2022 - frontiersin.org
Hepatitis B virus (HBV) infection in humans and its associated diseases are long-standing
problems. HBV can produce a large number of non-self-molecules during its life cycle, which …

[HTML][HTML] Emerging roles of lncRNAs regulating RNA-mediated type-I interferon signaling pathway

X Ji, W Meng, Z Liu, X Mu - Frontiers in Immunology, 2022 - frontiersin.org
The type-I interferon (IFN-I) signaling pathway plays pivot roles in defending against
pathogen invasion. Exogenous ssRNA and dsRNA could be immunogenic. RNA-mediated …

Heat shock-binding protein 21 regulates the innate immune response to viral infection

Y Xu, Q Yang, B Xue, X Wang, R Tian, R Deng… - Journal of …, 2022 - Am Soc Microbiol
The induction of interferons (IFNs) plays an important role in the elimination of invading
pathogens. Heat shock binding protein 21 (HBP21), first known as a molecular chaperone of …

[HTML][HTML] Long noncoding RNA expression rofiles elucidate the potential roles of lncRNA-XR_003496198 in duck hepatitis A virus type 1 infection

N Sui, R Zhang, Y Jiang, H Yu, G Xu, J Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Duck hepatitis A virus type 1 (DHAV-1) is a highly lethal virus that severely affects the duck
industry worldwide. Long noncoding RNAs (lncRNAs) exert crucial roles in pathogen …

Epigenetic regulation of RNA sensors: Sentinels of immune response

MI Khan, SM Nur, V Adhami, H Mukhtar - Seminars in Cancer Biology, 2022 - Elsevier
Living host system possess mechanisms like innate immune system to combat against
inflammation, stress singling, and cancer. These mechanisms are initiated by PAMP and …

[HTML][HTML] Lnc-ITM2C-1 and GPR55 Are Proviral Host Factors for Hepatitis C Virus

P Hu, J Wilhelm, GK Gerresheim, LA Shalamova… - Viruses, 2019 - mdpi.com
Multiple host factors are known to play important roles in hepatitis C virus (HCV) replication,
in immune responses induced by HCV infection, or in processes that facilitate virus escape …

Host Factors Modulate Virus-Induced IFN Production via Pattern Recognition Receptors

J Wang, Y Dong, X Zheng, H Ma, M Huang… - Journal of …, 2024 - Taylor & Francis
Innate immunity is the first line of defense in the human body, and it plays an important role
in defending against viral infection. Viruses are identified by different pattern-recognition …

[HTML][HTML] Long non-coding RNA-mediated regulation of the interferon response: a new perspective on a familiar theme

S Valadkhan, LM Plasek - Pathogens & immunity, 2018 - ncbi.nlm.nih.gov
The interferon (IFN) response is a critical and ubiquitous component of the innate immune
response to pathogens. Detailed studies in the last decades have elucidated the function of …