Introduction Sepsis-associated encephalopathy (SAE) and septic encephalitis (SE) are
associated with increased mortality, long-term cognitive impairment, and focal neurological …

Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Corticosteroids, such as hydrocortisone and dexamethasone, haveanti-inflammatory,
antifibrotic, andvasoconstrictiveeffects, which intensivists have been trying to leverage for …

Cushing's syndrome (CS), or chronic hypercortisolism, induces a variety of alterations in the
immune system, often leading to severe clinical complications such as sepsis and …

Acute lung injury (ALI) represents a serious heterogenous pulmonary disorder with high
mortality. Despite improved understanding of the pathophysiology, the efficacy of standard …

Background Sepsis occurs when an infection is complicated by organ failure. Sepsis may be
complicated by impaired corticosteroid metabolism. Thus, providing corticosteroids may …

Background Trials and study-level meta-analyses have failed to resolve the role of
corticosteroids in the management of patients with septic shock. Patient-level meta-analyses …

Purpose Acute respiratory distress syndrome (ARDS) is an acute and critical disease among
children and adults, and previous studies have shown that the administration of …

Importance Pituitary adenoma is the second most common primary brain tumor.
Perioperative hydrocortisone has been used for decades to avoid postoperative adrenal …

Objective Corticosteroids are a common option used in sepsis treatment. However, the
efficacy and potential risk of corticosteroids in septic patients have not been well assessed …