Role of non-coding RNAs in hepatocellular carcinoma progression: from classic to novel clinicopathogenetic implications
M Romeo, M Dallio, F Scognamiglio, L Ventriglia… - Cancers, 2023 - mdpi.com
Simple Summary Given the increasing incidence of hepatocellular carcinoma (HCC)
worldwide, a full comprehension of the molecular pathways supporting HCC onset and …
worldwide, a full comprehension of the molecular pathways supporting HCC onset and …
Mechanisms of resistance to immunotherapy in hepatocellular carcinoma
GF Manfredi, C Celsa, C John, C Jones… - Journal of …, 2023 - Taylor & Francis
Systemic treatment for advanced hepatocellular carcinoma (HCC) has been revolutionized
over the last few years following the approval of immune checkpoint inhibitors (ICI). Despite …
over the last few years following the approval of immune checkpoint inhibitors (ICI). Despite …
Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular …
Q Wu, X Li, M Long, X Xie, Q Liu - Scientific Reports, 2023 - nature.com
Histone lysine lactylation (Kla) plays a vital role in the tumorigenesis of hepatocellular
carcinoma (HCC). Hence, we focused on Kla-specific genes to select novel therapeutic …
carcinoma (HCC). Hence, we focused on Kla-specific genes to select novel therapeutic …
Advances in Histological and Molecular Classification of Hepatocellular Carcinoma
JH Choi, SN Thung - Biomedicines, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is a primary liver cancer characterized by hepatocellular
differentiation. HCC is molecularly heterogeneous with a wide spectrum of histopathology …
differentiation. HCC is molecularly heterogeneous with a wide spectrum of histopathology …
[HTML][HTML] Hepatocellular carcinoma immune microenvironment and check point inhibitors-current status
T Gupta, NS Jarpula - World Journal of Hepatology, 2024 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and has a
high mortality rate. The Barcelona Clinic Liver Cancer staging system in addition to tumor …
high mortality rate. The Barcelona Clinic Liver Cancer staging system in addition to tumor …
Targeting casein kinase 1 for cancer therapy: current strategies and future perspectives
NH Long, SJ Lee - Frontiers in Oncology, 2023 - frontiersin.org
Casein Kinase 1 (CK1) is a family of serine/threonine protein kinases that play a crucial role
in various cellular processes, including cell proliferation, survival, and metabolism. The …
in various cellular processes, including cell proliferation, survival, and metabolism. The …
[HTML][HTML] Wnt/β-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic target
Z Zhao, T Cui, F Wei, Z Zhou, Y Sun, C Gao… - Frontiers in …, 2024 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor and one
of the leading causes of cancer-related deaths worldwide. The Wnt/β-Catenin signaling …
of the leading causes of cancer-related deaths worldwide. The Wnt/β-Catenin signaling …
Inducing the Abscopal Effect in Liver Cancer Treatment: The Impact of Microwave Ablation Power Levels and PD-1 Antibody Therapy
C Liao, G Zhang, R Huang, L Zeng, B Chen, H Dai… - Pharmaceuticals, 2023 - mdpi.com
Microwave ablation (MWA) is an effective treatment for liver cancer (LC), but its impact on
distant tumors remains to be fully elucidated. This study investigated the abscopal effects …
distant tumors remains to be fully elucidated. This study investigated the abscopal effects …
Biological mechanisms of resistance to immune checkpoint inhibitors and overcoming this resistance: Challenges in medical oncology
Y Moskalenko - Regulatory Mechanisms in Biosystems, 2024 - medicine.dp.ua
Immune checkpoint inhibitors have opened up new possibilities in clinical oncology.
Monoclonal antibodies have shown their high clinical efficiency. They block CTLA-4, PD-1 …
Monoclonal antibodies have shown their high clinical efficiency. They block CTLA-4, PD-1 …