[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer

X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …

Circular RNA and its mechanisms in disease: from the bench to the clinic

B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …

[HTML][HTML] Circular RNAs in cancer: opportunities and challenges in the field

LS Kristensen, TB Hansen, MT Venø, J Kjems - Oncogene, 2018 - nature.com
Circular RNA (circRNA) is a novel member of the noncoding cancer genome with distinct
properties and diverse cellular functions, which is being explored at a steadily increasing …

[HTML][HTML] Circular RNAs in cancer

DH Bach, SK Lee, AK Sood - Molecular Therapy-Nucleic Acids, 2019 - cell.com
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …

CircRNAs and cancer: biomarkers and master regulators

E Arnaiz, C Sole, L Manterola, L Iparraguirre… - Seminars in cancer …, 2019 - Elsevier
Circular RNAs (circRNAs) are a novel class of regulatory RNAs that despite being relatively
abundant have only recently begun to be explored. There are many thousands of genes that …

[HTML][HTML] Circular RNA: a novel biomarker and therapeutic target for human cancers

B Lei, Z Tian, W Fan, B Ni - International journal of medical …, 2019 - ncbi.nlm.nih.gov
Circular (circ) RNAs, a newly recognized class of noncoding RNA, have been implicated in
the occurrence and development of several diseases, including neurological and …

[HTML][HTML] Circular RNA circ-ABCB10 promotes breast cancer proliferation and progression through sponging miR-1271

HF Liang, XZ Zhang, BG Liu, GT Jia… - American journal of …, 2017 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a key regulator in the development and progression of human
cancers, however its role in breast cancer tumorigenesis is not well understood. The present …

[HTML][HTML] Molecular roles and function of circular RNAs in eukaryotic cells

LM Holdt, A Kohlmaier, D Teupser - Cellular and Molecular Life Sciences, 2018 - Springer
Protein-coding and noncoding genes in eukaryotes are typically expressed as linear
messenger RNAs, with exons arranged colinearly to their genomic order. Recent advances …

[HTML][HTML] Emerging roles of circRNA in formation and progression of cancer

Y Yin, J Long, Q He, Y Li, Y Liao, P He, W Zhu - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are recently discovered as a special novel type of endogenous
noncoding RNAs (ncRNAs), which form a covalently closed continuous loop and are highly …

Circular RNA: an emerging non-coding RNA as a regulator and biomarker in cancer

B Chen, S Huang - Cancer letters, 2018 - Elsevier
Circular RNA (circRNA) is a type of covalently closed non-coding RNA that may regulate
gene expression in eukaryotes. The recent application of high-throughput RNA sequencing …