Investigating causality with fecal microbiota transplantation in rodents: applications, recommendations and pitfalls

CE Gheorghe, NL Ritz, JA Martin, HR Wardill… - Gut …, 2021 - Taylor & Francis
In recent years, studies investigating the role of the gut microbiota in health and diseases
have increased enormously–making it essential to deepen and question the research …

[HTML][HTML] Role of Interleukin-22 in ulcerative colitis

N Zhao, C Liu, N Li, S Zhou, Y Guo, S Yang… - Biomedicine & …, 2023 - Elsevier
Ulcerative Colitis (UC) is a chronic disease, in the progression of which an immune
overreaction may play an important role. IL-22 is a member of the IL-10 superfamily of …

Pharmacological inhibition of MALT1 protease leads to a progressive IPEX-like pathology

K Martin, U Junker, E Tritto, E Sutter… - Frontiers in …, 2020 - frontiersin.org
Genetic disruption or short-term pharmacological inhibition of MALT1 protease is effective in
several preclinical models of autoimmunity and B cell malignancies. Despite these …

Pharmacological inhibition of MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) induces ferroptosis in vascular smooth muscle cells

B Yan, D Belke, Y Gui, YX Chen, ZS Jiang… - Cell Death …, 2023 - nature.com
MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) is a human
paracaspase protein with proteolytic activity via its caspase-like domain. The …

Microbiomic and Metabolomic Analyses Unveil the Protective Effect of Saffron in a Mouse Colitis Model

G Singh, H Brim, Y Haileselassie, S Varma… - Current Issues in …, 2023 - mdpi.com
Despite the existence of effective drugs used to treat inflammatory bowel disease (IBD),
many patients fail to respond or lose response over time. Further, many drugs can carry …

The olfactory G protein-coupled receptor (Olfr-78/OR51E2) modulates the intestinal response to colitis

K Kotlo, AN Anbazhagan… - … of Physiology-Cell …, 2020 - journals.physiology.org
Olfactory receptor-78 (Olfr-78) is a recently identified G protein-coupled receptor activated by
short-chain fatty acids acetate and propionate. A suggested role for this receptor exists in the …

Impact of titanium dioxide nanoparticles on intestinal community in 2, 4, 6-trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of …

Y Gao, T Li, S Duan, L Lyu, Y Li, L Xu, Y Wang - Nanoscale, 2021 - pubs.rsc.org
Titanium dioxide nanoparticles (TiO2-NPs) are widely applied as additives in foods due to
their excellent whitening and brightening capability. Although the toxicity and antibacterial …

Potential role of MALT1 as a candidate biomarker of disease surveillance and treatment response prediction in inflammatory bowel disease patients

Z Wu, Y Bi - Journal of Clinical Laboratory Analysis, 2022 - Wiley Online Library
Background Mucosa‐associated lymphoid tissue lymphoma translocation protein 1 (MALT1)
regulates adaptive and innate immune responses in several inflammatory disease …

Post-translational modification of MALT1 and its role in B cell-and T cell-related diseases

YY Zhang, J Peng, XJ Luo - Biochemical Pharmacology, 2022 - Elsevier
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is a
multifunctional protein. MALT1 functions as an adaptor protein to assemble and recruit …

Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing

L Wittner, L Wagener, JJ Wiese, I Stolzer… - International journal of …, 2023 - mdpi.com
The paracaspase MALT1 is a crucial regulator of immune responses in various cellular
contexts. Recently, there is increasing evidence suggesting that MALT1 might represent a …