J Diniz Pereira, V Gomes Fraga… - Journal of …, 2021 - Wiley Online Library
Similar to dementia, the risk for developing type 2 diabetes mellitus (T2DM) increases with age, and T2DM also increases the risk for dementia, particularly Alzheimer's disease (AD) …
S Dong, Y Duan, Y Hu, Z Zhao - Translational neurodegeneration, 2012 - Springer
Alzheimer's disease (AD) is a common neurodegenerative disease characterized clinically by progressive deterioration of memory, and pathologically by histopathological changes …
Y Kitamura, R Usami, S Ichihara, H Kida… - Neurological …, 2017 - Taylor & Francis
Objectives: Alzheimer's disease (AD) is the most common cause of dementia in elderly persons. Since the pathology of AD develops slowly from a preclinical or early phase into a …
M Das, O Gursky - Lipids in Protein Misfolding, 2015 - Springer
Apolipoproteins are protein constituents of lipoproteins that transport cholesterol and fat in circulation and are central to cardiovascular health and disease. Soluble apolipoproteins …
Cholesterol levels have been repeatedly linked to Alzheimer's Disease (AD), suggesting that high levels could be detrimental, but this effect is likely attributed to Low‐Density Lipoprotein …
M Chen, W Xia - Journal of Alzheimer's Disease, 2020 - content.iospress.com
Background: Alzheimer's disease (AD) is the most prevalent form of dementia with two pathological hallmarks of tau-containing neurofibrillary tangles and amyloid-β protein (Aβ) …
CH Lee, CE Murrell, A Chu, X Pan - International Journal of Molecular …, 2023 - mdpi.com
The circadian rhythm is a 24 h internal clock within the body that regulates various factors, including sleep, body temperature, and hormone secretion. Circadian rhythm disruption is …
AB Andraski, SA Singh, H Higashi, LH Lee, M Aikawa… - JCI insight, 2023 - ncbi.nlm.nih.gov
Abstract Apolipoprotein A4's (APOA4's) functions on HDL in humans are not well understood. A unique feature of APOA4 is that it is an intestinal apolipoprotein secreted on …
Y Kim, J Kim, M Son, J Lee, I Yeo, KY Choi, H Kim… - Scientific reports, 2022 - nature.com
Alzheimer disease (AD) is a leading cause of dementia that has gained prominence in our aging society. Yet, the complexity of diagnosing AD and measuring its invasiveness poses …