Decades of study indicate that copper oral exposures are typically not a human health
concern. Ingesting high levels of soluble copper salts can cause acute gastrointestinal …

Background Nicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in
every living cell, is involved in a myriad of metabolic processes associated with cellular …

Highlights•Aging is the major risk factor for AMD.•The macula contains more than 60 kinds of
cells that may age at different rates.•The retinal aging in AMD is determined by its interplay …

BACKGROUND: We evaluated the amounts of amyloid beta (Aβ)) peptides in the central
nervous system (CNS) and in reservoirs outside the CNS and their potential impact on Aβ …

Amyloid β proteins and oxidative stress are believed to have central roles in the
development of Alzheimer's disease. Lipid membranes are among the most vulnerable …

The purpose of this book is to share current knowledge about the impact of ethnicity and
culture on dementing disorders. At first glance, the reader may wonder why this is the topic …

Background: Statins represent a class of medications widely prescribed to efficiently treat
dyslipidemia. These drugs inhibit 3-βhydroxy 3β-methylglutaryl Coenzyme A reductase …

Background: Heart disease and stroke are two of the major leading causes of death and
disability in the world. Mainly affecting the elderly population, heart disease and stroke are …

The hippocampus is a vulnerable and plastic brain structure that is damaged by a variety of
stimuli, eg hypoxia, hypoperfusion, hypoglycaemia, stress and seizures. Alzheimer's disease …

Alzheimer's disease is the most prevalent form of dementia. Neuropathogenesis is proposed
to be a result of the accumulation of amyloid beta peptides in the brain together with …