Recent Advances in Pyrimidine-Based Drugs
B Nammalwar, RA Bunce - Pharmaceuticals, 2024 - mdpi.com
Pyrimidines have become an increasingly important core structure in many drug molecules
over the past 60 years. This article surveys recent areas in which pyrimidines have had a …
over the past 60 years. This article surveys recent areas in which pyrimidines have had a …
Synthesis of Ribociclib Using Phase Transfer Catalysis and Ecofriendly Reducing Agent: Potential Method for Industrial Practice.
A Udayasri, DS Ramakrishna… - … of Molecular & …, 2024 - search.ebscohost.com
This research work reports the preparation of Ribociclib based on the green chemical
principles such as third principle (less hazardous chemical synthesis), fifth principle (Safer …
principles such as third principle (less hazardous chemical synthesis), fifth principle (Safer …
Selectivity Mechanism of Pyrrolopyridone Analogues Targeting Bromodomain 2 of Bromodomain-Containing Protein 4 from Molecular Dynamics Simulations
M Shi, X Zheng, Y Zhou, Y Yin, Z Lu, Z Zou, Y Hu… - ACS …, 2023 - ACS Publications
Bromodomain and extra-terminal domain (BET) proteins play an important role in epigenetic
regulation and are linked to several diseases; therefore, they are interesting targets. BET …
regulation and are linked to several diseases; therefore, they are interesting targets. BET …