Validation of biomarkers of aging
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
Early origins of health and disease risk: The case for investigating adverse exposures and biological aging in utero, across childhood, and into adolescence
L Etzel, P Garrett‐Petters… - Child Development …, 2023 - Wiley Online Library
In this article, we suggest that aging and development are two sides of the same coin, and
that developing a comprehensive understanding of health and disease risk requires …
that developing a comprehensive understanding of health and disease risk requires …
[HTML][HTML] Biological Aging Acceleration Due to Environmental Exposures: An Exciting New Direction in Toxicogenomics Research
Biological clock technologies are designed to assess the acceleration of biological age (B-
age) in diverse cell types, offering a distinctive opportunity in toxicogenomic research to …
age) in diverse cell types, offering a distinctive opportunity in toxicogenomic research to …
[HTML][HTML] Individual longitudinal changes in DNA-methylome identify signatures of early-life adversity and correlate with later outcome.
Adverse early-life experiences (ELA) affect a majority of the world's children. Whereas the
enduring impact of ELA on cognitive and emotional health is established, there are no tools …
enduring impact of ELA on cognitive and emotional health is established, there are no tools …
Maternal prenatal social experiences and offspring epigenetic age acceleration from birth to mid-childhood
Purpose Investigate associations of maternal social experiences with offspring epigenetic
age acceleration (EAA) from birth through mid-childhood among 205 mother-offspring dyads …
age acceleration (EAA) from birth through mid-childhood among 205 mother-offspring dyads …
Exploring perinatal biopsychosocial factors and epigenetic age in 1-year-old offspring
Background: Little is known about the determinants of epigenetic aging in pediatric
populations. Methods: Epigenetic age was estimated from 258 1-year-olds, using pediatric …
populations. Methods: Epigenetic age was estimated from 258 1-year-olds, using pediatric …
Association between maternal prenatal depressive symptoms and offspring epigenetic aging at 3-5 weeks
AT Folger, L Ding, K Yolton, RT Ammerman, H Ji… - Annals of …, 2024 - Elsevier
Epigenetic clocks are emerging as tools for assessing acceleration and deceleration of
biological age during childhood. Maternal depression during pregnancy may affect the …
biological age during childhood. Maternal depression during pregnancy may affect the …
[HTML][HTML] Within-subject changes in methylome profile identify individual signatures of early-life adversity, with a potential to predict neuropsychiatric outcome
AK Short, R Weber, N Kamei, CW Thai, H Arora… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Background. Adverse early-life experiences (ELA), including poverty, trauma and neglect,
affect a majority of the world's children. Whereas the impact of ELA on cognitive and …
affect a majority of the world's children. Whereas the impact of ELA on cognitive and …
Within-subject changes in DNA-methylome profile identify individual signatures of early-life adversity, with a potential to predict neuropsychiatric outcome.
AK Short, RL Weber, N Kamei, C Wilcox-Thai, H Arora… - bioRxiv, 2023 - biorxiv.org
Background: Adverse early-life experiences (ELA), including poverty, trauma and neglect,
affect a majority of world children. Whereas the impact of ELA on cognitive and emotional …
affect a majority of world children. Whereas the impact of ELA on cognitive and emotional …
[引用][C] Sex-Specific Associations between Prenatal Exposure to Di (2-ethylhexyl) Phthalate, Epigenetic Age Acceleration, and Susceptibility to Early Childhood Upper …
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