Alzheimer's disease, and breast and prostate cancer research: Translational failures and the importance to monitor outputs and impact of funded research

F Pistollato, C Bernasconi, J McCarthy, I Campia… - Animals, 2020 - mdpi.com
Simple Summary Noncommunicable diseases, such as Alzheimer's disease, and breast and
prostate cancer, are becoming increasingly prevalent in Western countries. To better …

Approaches for the integration of big data in translational medicine: single‐cell and computational methods

F Amirmahani, N Ebrahimi, F Molaei… - Annals of the New …, 2021 - Wiley Online Library
Translational medicine describes a bench‐to‐bedside approach that eventually converts
findings from basic scientific studies into real‐world clinical research. It encompasses new …

HFBD: a biomarker knowledge database for heart failure heterogeneity and personalized applications

H He, M Shi, Y Lin, C Zhan, R Wu, C Bi, X Liu… - …, 2021 - academic.oup.com
Motivation Heart failure (HF) is a cardiovascular disease with a high incidence around the
world. Accumulating studies have focused on the identification of biomarkers for HF …

Molecular landscape for risk prediction and personalized therapeutics of castration-resistant prostate cancer: at a glance

J Jian, X Wang, J Zhang, C Zhou, X Hou… - Frontiers in …, 2024 - frontiersin.org
Prostate cancer (PCa) is commonly occurred with high incidence in men worldwide, and
many patients will be eventually suffered from the dilemma of castration-resistance with the …

The aptamer functionalized nanocomposite used for prostate cancer diagnosis and therapy

X Feng, Y Zhu, F Wang, T Guo, X Dou… - Journal of …, 2022 - Wiley Online Library
Prostate cancer is one of the major malignancies that threaten men's health all over the
world. Due to the lack of specific symptoms and signs in the early stage, as well as the …

[PDF][PDF] 智能医学: 数据与模型驱动的医工融合

刘雷, 曾丽艳 - 医学信息学杂志, 2023 - yxxxx.ac.cn
目的/意义总结数据与模型驱动下智能医学发展的现状与趋势, 以提升临床医疗水平,
助推智能医学的发展与应用. 方法/过程介绍智能医学产生的背景, 阐述大数据融合与驱动 …

Elevated expression of glycerol-3-phosphate phosphatase as a biomarker of poor prognosis and aggressive prostate cancer

MA Lounis, V Ouellet, B Péant, C Caron, Z Li… - Cancers, 2021 - mdpi.com
Simple Summary A number of diseases, including cancers, can be diagnosed with
“biomarkers”, such as specific proteins, hormones, or mutations in some genes. These …

Polyamines as new potential biomarkers for differential diagnosis of prostate cancer and estimation of its aggressiveness

SP Zaletok, OO Klenov, VV Bentrad… - Experimental …, 2022 - exp-oncology.com.ua
Background: Prostate cancer (PCa) is one of the most common malignancies in older men.
The study of tissue markers of PCa can provide information about the state of proliferation …

Novel Gene Signatures for Prostate Cancer Detection: Network Centralitybased Screening with Experimental Validation

A Zhao, X Zhang, G Hu, X Wei, Y Huang… - Current …, 2023 - ingentaconnect.com
Background: Prostate cancer (PCa) is a kind of malignant tumor with high incidence among
males worldwide. The identification of novel biomarker signatures is therefore of clinical …

Nano-theranostics for the sensing, imaging and therapy of prostate cancers

DG Calatayud, S Neophytou, E Nicodemou… - Frontiers in …, 2022 - frontiersin.org
We highlight hereby recent developments in the emerging field of theranostics, which
encompasses the combination of therapeutics and diagnostics in a single entity aimed for an …