The role of complement activation in atherogenesis: the first 40 years

SI Vlaicu, A Tatomir, V Rus, AP Mekala, PA Mircea… - Immunologic …, 2016 - Springer
The pathogenesis of atherosclerotic inflammation is a multi-step process defined by the
interweaving of excess modified lipid particles, monocyte-macrophages populations, and …

Pravastatin promotes endothelial colony-forming cell function, angiogenic signaling and protein expression in vitro

N Meyer, L Brodowski, K Richter… - Journal of Clinical …, 2021 - mdpi.com
Endothelial dysfunction is a primary feature of several cardiovascular diseases. Endothelial
colony-forming cells (ECFCs) represent a highly proliferative subtype of endothelial …

Vitamin D improves endothelial barrier integrity and counteracts inflammatory effects on endothelial progenitor cells

B Schröder‐Heurich, S von Hardenberg… - The FASEB …, 2019 - Wiley Online Library
Endothelial colony‐forming cells (ECFCs), a proliferative subpopulation of endothelial
progenitor cells, are involved in angiogenesis and endothelial repair. In this study, we …

mTORC2 facilitates endothelial cell senescence by suppressing Nrf2 expression via the Akt/GSK-3β/C/EBPα signaling pathway

H Yang, H Hong, W Luo, C Dai, X Chen… - Acta Pharmacologica …, 2018 - nature.com
Vascular endothelial cell senescence is a leading cause of age-associated and vascular
diseases. Mammalian target of rapamycin complex 2 (mTORC2) is a conserved …

Nano-medicine and vascular endothelial dysfunction: options and delivery strategies

G Taneja, A Sud, N Pendse, B Panigrahi… - Cardiovascular …, 2019 - Springer
The endothelium is a thin innermost layer of flat cells which release various mediators
including endothelin-1 (ET-1), prostanoids, von Willebrand factor (vWF) and endothelium …

Role of p90RSK in kidney and other diseases

L Lin, SA White, K Hu - International journal of molecular sciences, 2019 - mdpi.com
The 90 kDa ribosomal s6 kinases (RSKs) are a group of serine/threonine kinases consisting
of 4 RSK isoforms (RSK1-4), of which RSK1 is also designated as p90RSK. p90RSK plays …

Vitexin protects against high glucose-induced endothelial cell apoptosis and oxidative stress via Wnt/β-catenin and Nrf2 signalling pathway

S Zhang, S Jin, S Zhang, YY Li, H Wang… - … of Physiology and …, 2024 - Taylor & Francis
Vitexin, a polyphenolic flavonoid, has been reported to be traditionally applied in the
treatment of diabetes, cancer and cardiovascular diseases. Objective The aim of this study …

Regulation of transcription factors by reactive oxygen species and nitric oxide in vascular physiology and pathology

S Kohlgrüber, A Upadhye, N Dyballa-Rukes… - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Cardiovascular diseases are the main cause of death worldwide and pose an
immense economical burden. In most cases, the underlying problem is vascular occlusion …

Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV 4 channels

D Peixoto‐Neves, Q Wang… - British Journal of …, 2015 - Wiley Online Library
Background and Purpose Eugenol, a vanilloid molecule found in some dietary plants,
relaxes vasculature in part via an endothelium‐dependent process; however, the …

Homocysteine induced a calcium‐mediated disruption of mitochondrial function and dynamics in endothelial cells

L Chen, T Xu, Y Qiu, N Liu, X Ke, L Fang… - … of Biochemical and …, 2021 - Wiley Online Library
Homocysteine (Hcy) is a sulfur‐containing amino acid that originated in methionine
metabolism and the elevated level of Hcy in plasma is considered to be an independent risk …