[HTML][HTML] The genetic basis of abdominal aortic aneurysms: a review

RM Sandford, MJ Bown, NJ London… - European Journal of …, 2007 - Elsevier
INTRODUCTION: The pathogenesis of abdominal aortic aneurysm (AAA) remains poorly
understood, however significant evidence has emerged in recent years to suggest a chronic …

CCR5Δ32 in Brazil: Impacts of a european genetic variant on a highly admixed population

B Kulmann-Leal, JH Ellwanger, JAB Chies - Frontiers in Immunology, 2021 - frontiersin.org
The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

The CCR5-Delta32 genetic polymorphism and HIV-1 infection susceptibility: a meta-analysis

J Ni, D Wang, S Wang - Open Medicine, 2018 - degruyter.com
The CC chemokine receptor 5 (CCR5) is a chemokine receptor which is widely expressed in
several immune cells involved in the inflammatory responses. Previous published studies …

Frequency of CCR5delta32 in Brazilian populations

AE Vargas, AR Marrero, FM Salzano… - Brazilian Journal of …, 2006 - SciELO Brasil
A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested
for the CCR5delta32 allele, which is known to influence susceptibility to HIV-1 infection. The …

CCR5 Δ32 Polymorphism: Associated with Gallbladder Cancer Susceptibility

A Srivastava, SN Pandey… - … journal of immunology, 2008 - Wiley Online Library
Inflammation of gallbladder is an established risk factor for gallbladder cancer (GBC)
pathogenesis. Chemokine receptors play crucial role in antitumour immunity and are …

Metabolomics as an Approach to Characterise the Contrasting Roles of CCR5 in the Presence and Absence of Disease

A Rautenbach, AA Williams - International journal of molecular sciences, 2020 - mdpi.com
Chemokine receptors such as CC chemokine receptor 5 (CCR5) are activated through
interaction with their ligands and are well known for their role in chemotaxis and signal …

Frequency of the CCR5-delta32 allele in Brazilian populations: A systematic literature review and meta-analysis

WHV Silva-Carvalho, RR de Moura… - Infection, Genetics and …, 2016 - Elsevier
The CCR5 is a chemokine receptor widely expressed by several immune cells that are
engaged in inflammatory responses. Some populations have individuals exhibiting a 32 bp …

Faster HIV-1 disease progression among Brazilian individuals recently infected with CXCR4-utilizing strains

MCA Sucupira, S Sanabani, RM Cortes, MTM Giret… - PloS one, 2012 - journals.plos.org
Introduction Primary HIV infection is usually caused by R5 viruses, and there is an
association between the emergence of CCXR4-utilizing strains and faster disease …

CCR5∆ 32 and SDF1 3′ A: Gene Variants, Expression and Influence on Biological Markers for the Clinical Progression to AIDS among HIV-1 Virus Controllers in a …

ÉRG Lima, MAF Queiroz, SS Lima… - International Journal of …, 2023 - mdpi.com
CCR5Δ32 and SDF1-3′ A polymorphisms were investigated in a cohort of viremia
controllers, without the use of therapy, along with their influence on CD4+ T lymphocytes …

Functional genetic polymorphisms of monocyte chemoattractant protein 1 and CC chemokine receptor type 2 in ischemic stroke

A Arakelyan, R Zakharyan… - Journal of Interferon & …, 2014 - liebertpub.com
Recent findings indicated that monocyte chemoattractant protein 1 (MCP1) and its CC
chemokine receptor type 2 (CCR2) play a key role in ischemic stroke (IS) progression. This …