[HTML][HTML] COVID-19 update: The race to therapeutic development

JD Twomey, S Luo, AQ Dean, WP Bozza, A Nalli… - Drug Resistance …, 2020 - Elsevier
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), represents an unprecedented challenge to global public health. At the time …

[HTML][HTML] A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling

D Hasan, A Shono, CK van Kalken, PJ van der Spek… - Purinergic …, 2022 - Springer
Hyperinflammation plays an important role in severe and critical COVID-19. Using
inconsistent criteria, many researchers define hyperinflammation as a form of very severe …

[HTML][HTML] Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation

P Saas, M Vetter, M Maraux, F Bonnefoy… - Frontiers in …, 2022 - frontiersin.org
Several chronic inflammatory diseases are associated with non-resolving inflammation.
Conventional anti-inflammatory drugs fail to completely cure these diseases. Resolution …

Identification of distinct clinical subphenotypes in critically ill patients with COVID-19

CR Vasquez, S Gupta, TA Miano, M Roche, J Hsu… - Chest, 2021 - Elsevier
Background Subphenotypes have been identified in patients with sepsis and ARDS and are
associated with different outcomes and responses to therapies. Research Question Can …

[HTML][HTML] Isolation of a human SARS-CoV-2 neutralizing antibody from a synthetic phage library and its conversion to fluorescent biosensors

H Li, B Zhu, B Li, L Chen, X Ning, H Dong, J Liang… - Scientific Reports, 2022 - nature.com
Since late 2019, the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) and the resultant spread of COVID-19 have given rise to a worldwide health crisis …

[HTML][HTML] Familial Mediterranean fever and COVID-19: friends or foes?

A Stella, M Lamkanfi, P Portincasa - Frontiers in immunology, 2020 - frontiersin.org
Familial Mediterranean Fever (FMF) and COVID-19 show a remarkable overlap of clinical
symptoms and similar laboratory findings. Both are characterized by fever, abdominal/chest …

COVID-19 and systemic sclerosis: rising to the challenge of a pandemic

CP Denton, C Campochiaro, C Bruni… - … of Scleroderma and …, 2021 - journals.sagepub.com
COVID-19, caused by infection of the novel coronavirus SARS-CoV-2, has caused a
pandemic of enormous impact that has challenged healthcare and political system …

[HTML][HTML] In vivo and ex vivo mitochondrial function in COVID-19 patients on the intensive care unit

LWJM Streng, CJ de Wijs, NJH Raat, PAC Specht… - Biomedicines, 2022 - mdpi.com
Mitochondrial dysfunction has been linked to disease progression in COVID-19 patients.
This observational pilot study aimed to assess mitochondrial function in COVID-19 patients …

[HTML][HTML] Targeting Specific Checkpoints in the Management of SARS-CoV-2 Induced Cytokine Storm

A Rabiu Abubakar, R Ahmad, AB Rowaiye, S Rahman… - Life, 2022 - mdpi.com
COVID-19-infected patients require an intact immune system to suppress viral replication
and prevent complications. However, the complications of SARS-CoV-2 infection that led to …

Obesitas sebagai faktor risiko keparahan pada COVID-19

NW Aqmarina, ED Risanti… - Prosiding University …, 2021 - repository.urecol.org
Obesitas diketahui sebagai peradangan kronis derajat rendah. Hal ini menjadi faktor yang
dapat menyebabkan keparahan pada gejala COVID-19. Gejala COVID-19 dinyatakan …