Circulating cellular clusters are associated with thrombotic complications and clinical outcomes in COVID-19

A Dorken-Gallastegi, Y Lee, G Li, H Li, L Naar, X Li… - Iscience, 2023 - cell.com
We sought to study the role of circulating cellular clusters (CCC)–such as circulating
leukocyte clusters (CLCs), platelet-leukocyte aggregates (PLA), and platelet-erythrocyte …

Emetine is not ipecac: considerations for its use as treatment for SARS-CoV2

MD Bleasel, GM Peterson - Pharmaceuticals, 2020 - mdpi.com
Emetine is a potent antiviral that acts on many viruses in the low-nM range, with several
studies in animals and humans demonstrating antiviral activity. Historically, emetine was …

Insights into COVID-19: Perspectives on Drug Remedies and Host Cell Responses

AM Awad, K Hansen, D Del Rio, D Flores… - Biomolecules, 2023 - mdpi.com
In light of the COVID-19 global pandemic caused by SARS-CoV-2, ongoing research has
centered on minimizing viral spread either by stopping viral entry or inhibiting viral …

Early antibody responses associated with survival in COVID19 patients

ZH Zhou, S Dharmarajan, M Lehtimaki… - PLoS …, 2021 - journals.plos.org
Neutralizing antibodies to the SARS CoV-2 spike proteins have been issued Emergency
Use Authorizations and are a likely mechanism of vaccines to prevent COVID-19. However …

[HTML][HTML] The fight against COVID-19: Striking a balance in the renin–angiotensin system

AQ Dean, WP Bozza, JD Twomey, S Luo, A Nalli… - Drug discovery today, 2021 - Elsevier
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
enters host cells by interacting with membrane-bound angiotensin-converting enzyme 2 …

Obesitas Mempengaruhi Tingkat Keparahan Pasien COVID-19

A Adimara, K Prahasanti… - Jurnal Ilmiah …, 2021 - repository.um-surabaya.ac.id
Penyakit COVID-19 telah menjadi pandemi global sejak Desember 2019. Menurut WHO,
hingga 28 September 2020, sudah ada 33.137. 748 kasus yang dikonfirmasi di seluruh …

Cytokines and Chemokines in Breastmilk of SARS-CoV-2 Infected or COVID-19 Vaccinated Mothers

F Trofin, OS Dorneanu, D Constantinescu, EV Nastase… - Vaccines, 2022 - mdpi.com
Introduction: The COVID-19 disease and anti-SARS-CoV-2 vaccination were accompanied
by alterations in several inflammatory markers. The aim of our research was to check to what …

The effect of tocilizumab on cytokine release syndrome in COVID-19 patients

C de Caceres, R Martinez, P Bachiller, L Marin… - Pharmacological …, 2020 - Springer
Background This study was aimed to assess the efficacy and safety of tocilizumab (TCZ) and
to investigate the factors related to the progress and mortality of patients with a secondary …

Mechanisms of immunothrombosis by SARS-CoV-2

MT Hernández-Huerta, AD Pérez-Santiago… - Biomolecules, 2021 - mdpi.com
SARS-CoV-2 contains certain molecules that are related to the presence of
immunothrombosis. Here, we review the pathogen and damage-associated molecular …

[HTML][HTML] The adaptation of SARS-CoV-2 to humans

E Tosta - Memórias do Instituto Oswaldo Cruz, 2022 - SciELO Brasil
The process of adaptation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) to humans probably had started decades ago, when its ancestor diverged from the bat …