[HTML][HTML] Regulated cell death (RCD) in cancer: key pathways and targeted therapies

F Peng, M Liao, R Qin, S Zhu, C Peng, L Fu… - Signal transduction and …, 2022 - nature.com
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

[HTML][HTML] The interaction between ferroptosis and inflammatory signaling pathways

Y Chen, ZM Fang, X Yi, X Wei, DS Jiang - Cell death & disease, 2023 - nature.com
Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …

[HTML][HTML] Advances in mechanism and regulation of PANoptosis: Prospects in disease treatment

P Zhu, ZR Ke, JX Chen, SJ Li, TL Ma… - Frontiers in …, 2023 - frontiersin.org
PANoptosis, a new research hotspot at the moment, is a cell death pattern in which
pyroptosis, apoptosis, and necroptosis all occur in the same cell population. In essence …

[HTML][HTML] The road from AKI to CKD: molecular mechanisms and therapeutic targets of ferroptosis

R Guo, J Duan, S Pan, F Cheng, Y Qiao, Q Feng… - Cell death & …, 2023 - nature.com
Acute kidney injury (AKI) is a prevalent pathological condition that is characterized by a
precipitous decline in renal function. In recent years, a growing body of studies have …

The applications of nanozymes in cancer therapy: based on regulating pyroptosis, ferroptosis and autophagy of tumor cells

Y Zhang, W Yu, M Chen, B Zhang, L Zhang, P Li - Nanoscale, 2023 - pubs.rsc.org
Nanozymes are nanomaterials with catalytic properties similar to those of natural enzymes,
and they have recently been collectively identified as a class of innovative artificial enzymes …

[HTML][HTML] Apoptosis regulators bcl-2 and caspase-3

P Hussar - Encyclopedia, 2022 - mdpi.com
Definition Apoptosis, programmed cell death, has a central role in developmental biology
and in maintaining the equilibrium of renewing tissues. A founding member of the Bcl-2 …

[HTML][HTML] Disulfidptosis-associated LncRNAs index predicts prognosis and chemotherapy drugs sensitivity in cervical cancer

L Liu, J Liu, Q Lyu, J Huang, Y Chen, C Feng, Y Liu… - Scientific reports, 2023 - nature.com
Disulfidptosis is a newly discovered form of cell death. Not yet clearly classified as
programmed cell death or accidental cell death. This study aimed to create a novel …

[HTML][HTML] Ferroptosis, necroptosis, and pyroptosis in the occurrence and development of ovarian cancer

C Zhang, N Liu - Frontiers in immunology, 2022 - frontiersin.org
Ovarian cancer (OC) is one of the most common malignancies that causes death in women
and is a heterogeneous disease with complex molecular and genetic changes. Because of …

Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model

D Ye, Y Xu, Y Shi, M Fan, P Lu, X Bai… - Journal of Pineal …, 2022 - Wiley Online Library
Acute ocular hypertension (AOH) is the most important characteristic of acute glaucoma,
which can lead to retinal ganglion cell (RGC) death and permanent vision loss. So far …

[HTML][HTML] Pyroptosis and degenerative diseases of the elderly

J Zhou, J Qiu, Y Song, T Liang, S Liu, C Ren… - Cell Death & …, 2023 - nature.com
Pyroptosis is a recently described mechanism of programmed cell death mediated by
proteins of the gasdermin family. Widely recognized signaling cascades include the …