[HTML][HTML] Pathophysiology of COVID-19-associated acute kidney injury
Although respiratory failure and hypoxaemia are the main manifestations of COVID-19,
kidney involvement is also common. Available evidence supports a number of potential …
kidney involvement is also common. Available evidence supports a number of potential …
[HTML][HTML] The drug repurposing for COVID-19 clinical trials provide very effective therapeutic combinations: lessons learned from major clinical studies
SARS-CoV-2 has spread across the globe in no time. In the beginning, people suffered due
to the absence of efficacious drugs required to treat severely ill patients. Nevertheless, still …
to the absence of efficacious drugs required to treat severely ill patients. Nevertheless, still …
[PDF][PDF] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
K Westendorf, S Žentelis, L Wang, D Foster… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
[HTML][HTML] Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
In a randomized clinical trial of 86 hospitalized COVID-19 patients comparing standard care
to treatment with 300mL convalescent plasma containing high titers of neutralizing SARS …
to treatment with 300mL convalescent plasma containing high titers of neutralizing SARS …
Whole inactivated virus and protein-based COVID-19 vaccines
PJ Hotez, ME Bottazzi - Annual review of medicine, 2022 - annualreviews.org
The rapid development and deployment of mRNA and adenovirus-vectored vaccines
against coronavirus disease 2019 (COVID-19) continue to astound the global scientific …
against coronavirus disease 2019 (COVID-19) continue to astound the global scientific …
[HTML][HTML] Developing recombinant antibodies by phage display against infectious diseases and toxins for diagnostics and therapy
KDR Roth, EV Wenzel, M Ruschig, S Steinke… - Frontiers in cellular …, 2021 - frontiersin.org
Antibodies are essential molecules for diagnosis and treatment of diseases caused by
pathogens and their toxins. Antibodies were integrated in our medical repertoire against …
pathogens and their toxins. Antibodies were integrated in our medical repertoire against …
A Glycosylated RBD protein induces enhanced neutralizing antibodies against omicron and other variants with improved protection against SARS-CoV-2 infection
ABSTRACT SARS-CoV-2 has mutated frequently since its first emergence in 2019.
Numerous variants, including the currently emerging Omicron variant, have demonstrated …
Numerous variants, including the currently emerging Omicron variant, have demonstrated …
[HTML][HTML] Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …
infected and nearly six million dead worldwide, making it the most significant pandemic …
[HTML][HTML] Protective roles and protective mechanisms of neutralizing antibodies against SARS-CoV-2 infection and their potential clinical implications
EC Abebe, TA Dejenie - Frontiers in immunology, 2023 - frontiersin.org
Neutralizing antibodies (NAbs) are central players in the humoral immunity that defends the
body from SARS-CoV-2 infection by blocking viral entry into host cells and neutralizing their …
body from SARS-CoV-2 infection by blocking viral entry into host cells and neutralizing their …
[HTML][HTML] Effective vaccination strategy using SARS-CoV-2 spike cocktail against Omicron and other variants of concern
Abstract The SARS-CoV-2 Omicron variant harbors more than 30 mutations in its spike (S)
protein. Circulating Omicron subvariants, particularly BA5 and other variants of concern …
protein. Circulating Omicron subvariants, particularly BA5 and other variants of concern …