Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; an updated review

S Zanganeh, N Goodarzi, M Doroudian… - Reviews in Medical …, 2022 - Wiley Online Library
COVID‐19 has spread swiftly throughout the world posing a global health emergency. The
significant numbers of deaths attributed to this pandemic have researchers battling to …

Therapeutic role of neutralizing antibody for the treatment against SARS-CoV-2 and its emerging variants: a clinical and pre-clinical perspective

M Bhattacharya, S Chatterjee, B Mallik, AR Sharma… - Vaccines, 2022 - mdpi.com
Since early 2020, the entire world has been facing a disastrous outbreak of the SARS-CoV-2
virus, with massive reporting of death and infections per day. Medical practitioners adopted …

Primary exposure to SARS-CoV-2 via infection or vaccination determines mucosal antibody-dependent ACE2 binding inhibition

J Fröberg, VJCH Koomen… - The Journal of …, 2024 - academic.oup.com
Background Mucosal antibodies play a critical role in preventing SARS-CoV-2 infections or
reinfections by blocking the interaction of the receptor-binding domain (RBD) with the …

The rapid adaptation of SARS-CoV-2–rise of the variants: transmission and resistance

SM Soh, Y Kim, C Kim, US Jang, HR Lee - Journal of Microbiology, 2021 - Springer
The causative factor of COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is continuously mutating. Interestingly, identified mutations mainly occur in the spike …

[HTML][HTML] COVID-19 vaccine decisions: considering the choices and opportunities

PJ Hotez, T Nuzhath, T Callaghan, B Colwell - Microbes and Infection, 2021 - Elsevier
In the coming months, most American adults will have the opportunity to receive at least one
of up to five different COVID-19 vaccines produced by Operation Warp Speed and released …

Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study

K Qin, K Honjo, S Sherrill-Mix, W Liu, RM Stoltz… - PLoS …, 2023 - journals.plos.org
Background Patients with chronic lymphocytic leukemia (CLL) have reduced seroconversion
rates and lower binding antibody (Ab) and neutralizing antibody (NAb) titers than healthy …

From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access

PJ Hotez, R Adhikari, WH Chen, YL Chen… - Expert Review of …, 2023 - Taylor & Francis
Introduction The development of a yeast-expressed recombinant protein-based vaccine
technology co-developed with LMIC vaccine producers and suitable as a COVID-19 vaccine …

[HTML][HTML] Prediction and evolution of the molecular fitness of SARS-CoV-2 variants: introducing SpikePro

F Pucci, M Rooman - Viruses, 2021 - mdpi.com
The understanding of the molecular mechanisms driving the fitness of the SARS-CoV-2 virus
and its mutational evolution is still a critical issue. We built a simplified computational model …

A urinary proteomic landscape of COVID-19 progression identifies signaling pathways and therapeutic options

Y Liu, L Song, N Zheng, J Shi, H Wu, X Yang… - Science China Life …, 2022 - Springer
Signaling pathway alterations in COVID-19 of living humans as well as therapeutic targets of
the host proteins are not clear. We analyzed 317 urine proteomes, including 86 COVID-19 …

SARS-CoV-2: outline, prevention, and decontamination

E Janik, M Bartos, M Niemcewicz, L Gorniak, M Bijak - Pathogens, 2021 - mdpi.com
The new coronavirus began to spread around the world in late 2019. Initially, it was found
only in China, but in the following days there were reported cases of infections in other …