Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants

Q Li, F Humphries, RC Girardin, A Wallace… - Frontiers in …, 2022 - frontiersin.org
Anti-COVID antibody therapeutics have been developed but not widely used due to their
high cost and escape of neutralization from the emerging variants. Here, we describe the …

Structural and energetic profiling of SARS-CoV-2 antibody recognition and the impact of circulating variants

R Yin, JD Guest, G Taherzadeh, R Gowthaman, I Mittra… - bioRxiv, 2021 - biorxiv.org
The SARS-CoV-2 pandemic highlights the need for a detailed molecular understanding of
protective antibody responses. This is underscored by the emergence and spread of SARS …

COVID-19 patient serum less potently inhibits ACE2-RBD binding for various SARS-CoV-2 RBD mutants

D Junker, A Dulovic, M Becker, TR Wagner, PD Kaiser… - medRxiv, 2021 - medrxiv.org
As global vaccination campaigns against SARS-CoV-2 proceed, there is particular interest
in the longevity of immune protection, especially with regard to increasingly infectious virus …

[HTML][HTML] SARS-CoV-2 mRNA vaccination exposes progressive adaptive immune dysfunction in patients with chronic lymphocytic leukemia

K Qin, K Honjo, S Sherrill-Mix, W Liu, R Stoltz… - medRxiv, 2022 - ncbi.nlm.nih.gov
Chronic lymphocytic leukemia (CLL) patients have lower seroconversion rates and antibody
titers following SARS-CoV-2 vaccination, but the reasons for this diminished response are …

[HTML][HTML] Performance of the Roche/Snibe electrochemiluminescent anti-SARS-COV-2 spike assays compared to the Roche/Abbott IgG nucleocapsid and Abbott IgM …

CS Lau, MS Wong, SP Hoo, PY Heng, SK Phua… - Practical Laboratory …, 2021 - Elsevier
Abstract Introduction We evaluated the Roche Elecsys Anti-SARS-CoV-2 and Snibe SARS-
CoV-2 S-RBD IgG spike chemiluminescent immunoassays and compared them to existing …

Nanoarchitectonics: role of nanomaterials in vaccination strategies for curbing SARs-CoV-2/COVID-19

I Zulfiqar, A Wahab, MU Saeed, N Hussain… - …, 2022 - eaapublishing.org
With the exponential rise in infections by CoV-2 and the scarcity of antiviral therapeutics, the
development of an effective vaccine for the SARS CoV-2 is critical. The emerging pandemic …

Quantifying post-vaccination protective anti-SARS-CoV-2 IgG antibodies in blood and saliva with a fully automated, high throughput digital immunoassay

JM Johnson, SC Fernandes, DL Wuelfing… - medRxiv, 2022 - medrxiv.org
Background Antibodies induced by COVID-19 vaccination have been shown to wane over
time. Current tests for assessing virus-neutralizing antibodies are complex and time …

Neutralizing activity to SARS‐CoV‐2 in 1.2 to 10.0 month convalescent plasma samples of COVID‐19: A transversal surrogate in vitro study performed in Quito …

B Villacrés‐Granda, E Paz, MJ Burbano… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) infection, was first reported in Wuhan, China, in …

Лиганды и носители для улучшения иммунной активности: механизмы действия и перспективы применения в медицине и биотехнологии

СС Гогина, АМ Стойнова - Медицинская иммунология, 2023 - mimmun.ru
Аннотация Статья посвящена обзору исследований, посвященных роли антител,
цитокинов, белков комплемента, молекул основного комплекса гистосовместимости …

Development of a Novel SARS-CoV-2 Immune Complex Vaccine Candidate (CRCx) with Broad Immune Responses: A Preclinical Trial in Animal Model

S Salah, A Mubarki, K Zayed, K Omar - bioRxiv, 2022 - biorxiv.org
Background The ongoing pandemic of COVID-19, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), poses a serious threat to global public health and …