Multifaced roles of the long non-coding RNA DRAIC in cancer progression
K Sakurai, H Ito - Life Sciences, 2024 - Elsevier
Long non-coding RNAs (lncRNA) are functional RNAs, with over 200 nucleotides in length
and lacking protein-coding potential. Studies have indicated that lncRNAs are important …
and lacking protein-coding potential. Studies have indicated that lncRNAs are important …
Efficient enzyme-free method to assess the development and maturation of the innate and adaptive immune systems in the mouse colon
N Lassoued, A Yero, MA Jenabian, R Soret, N Pilon - Scientific Reports, 2024 - nature.com
Researchers who aim to globally analyze the gastrointestinal immune system via flow
cytometry have many protocol options to choose from, with specifics generally tied to gut …
cytometry have many protocol options to choose from, with specifics generally tied to gut …
[HTML][HTML] A targeted CRISPR-Cas9 mediated F0 screen identifies genes involved in establishment of the enteric nervous system
R Moreno-Campos, EW Singleton, RA Uribe - Plos one, 2024 - journals.plos.org
The vertebrate enteric nervous system (ENS) is a crucial network of enteric neurons and glia
resident within the entire gastrointestinal tract (GI). Overseeing essential GI functions such …
resident within the entire gastrointestinal tract (GI). Overseeing essential GI functions such …
Association between gut microbiota and Hirschsprung disease: a bidirectional two-sample Mendelian randomization study
W Liu, H Yan, W Jia, J Huang, Z Fu, W Xu… - Frontiers in …, 2024 - frontiersin.org
Background Several studies have pointed to the critical role of gut microbiota (GM) and their
metabolites in Hirschsprung disease (HSCR) pathogenesis. However, the detailed causal …
metabolites in Hirschsprung disease (HSCR) pathogenesis. However, the detailed causal …
Ischemia promotes hypertrophic nerve trunk formation and enteric neuron cell death in Hirschsprung's disease
D Xu, W Liang, C Lan, L Li, W Zhong, M Yao, X Zuo… - medRxiv, 2024 - medrxiv.org
Objective: Enteric nervous system dysfunction is linked to digestive and neurological
disorders. Hirschsprung's disease (HSCR) is characterized by the loss of enteric neuron …
disorders. Hirschsprung's disease (HSCR) is characterized by the loss of enteric neuron …
Clinical characteristics and influence of postoperative Hirschsprung-associated enterocolitis: retrospective study at a tertiary children's hospital
W Feng, B Zhang, L Fan, A Song, J Hou, X Die… - Pediatric Surgery …, 2024 - Springer
Purpose To explore the influence of postoperative Hirschsprung-associated enterocolitis
(post-HAEC) on long-term outcomes and to identify risk factors of post-HAEC. Methods The …
(post-HAEC) on long-term outcomes and to identify risk factors of post-HAEC. Methods The …
miR-146b-5p Regulates the Enteric Nervous System Development in Hirschsprung Disease via Targeting RET Pathway
B Zhang, J Yang, A Song, W Feng, Z Guo - Biochemical Genetics, 2024 - Springer
The objective of the study is to investigate how miR-146b-5p might contribute to the etiology
of HSCR. The study investigated the expression levels of miRNA, mRNA, and proteins in …
of HSCR. The study investigated the expression levels of miRNA, mRNA, and proteins in …
Anorectal Manometry in Pediatric Colorectal Surgical Care
JC Wheeler, SS Short, MD Rollins - Children, 2024 - mdpi.com
Background: Pediatric colorectal specialists care for patients with a variety of defecation
disorders. Anorectal (AR) manometry testing is a valuable tool in the diagnosis and …
disorders. Anorectal (AR) manometry testing is a valuable tool in the diagnosis and …
Translation and validation of the Hirschsprung and anorectal malformation quality of life (HAQL) questionnaire in a Danish Hirschsprung population
K Gosvig, SS Jensen, H Sjölander, NH Hansen… - Pediatric Surgery …, 2024 - Springer
Background Hirschsprung's disease (HD) may result in an impaired quality of life (QoL) due
to bowel problems, postoperative complications and other health-related issues. The …
to bowel problems, postoperative complications and other health-related issues. The …
[HTML][HTML] Chronic Constipation Unmasking as Hirschsprung Disease in a Preadolescent: Delayed Presentation or Delayed Diagnosis?
A Bhargava, K Khedkar - Cureus, 2024 - ncbi.nlm.nih.gov
Hirschsprung disease, a rare genetic disorder affecting the enteric nervous system, is
characterized by the absence of ganglion cells in the myenteric plexus. Typically identified in …
characterized by the absence of ganglion cells in the myenteric plexus. Typically identified in …