[HTML][HTML] Role of microRNAs in alcohol-induced liver disorders and non-alcoholic fatty liver disease

JL Torres, I Novo-Veleiro, L Manzanedo… - World journal of …, 2018 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs that regulate multiple physiological and
pathological functions through the modulation of gene expression at the post-transcriptional …

Circular RNA as an epigenetic regulator in chronic liver diseases

X Zeng, X Yuan, Q Cai, C Tang, J Gao - Cells, 2021 - mdpi.com
Circular RNA (circRNA) is a type of non-coding RNA characterized by a covalently closed
continuous loop. CircRNA is generated by pre-mRNA through back-splicing and is probably …

Hepatotoxic effects of hexafluoropropylene oxide trimer acid (HFPO-TA), a novel perfluorooctanoic acid (PFOA) alternative, on mice

N Sheng, Y Pan, Y Guo, Y Sun… - Environmental science & …, 2018 - ACS Publications
As an alternative to perfluorooctanoic acid (PFOA), hexafluoropropylene oxide trimer acid
(HFPO-TA) has been increasingly used for fluoropolymer manufacture in recent years. Its …

Antagonizing circRNA_002581–miR-122–CPEB1 axis alleviates NASH through restoring PTEN–AMPK–mTOR pathway regulated autophagy

X Jin, J Gao, R Zheng, M Yu, Y Ren, T Yan… - Cell Death & …, 2020 - nature.com
Circular RNAs (circRNAs) have been shown to play critical roles in cancer biology, but their
functions in nonalcoholic steatohepatitis (NASH) remain unexplored. Full length of …

[HTML][HTML] Knock-down of circular RNA H19 induces human adipose-derived stem cells adipogenic differentiation via a mechanism involving the polypyrimidine tract …

Y Zhu, W Gui, X Lin, H Li - Experimental cell research, 2020 - Elsevier
Abstract Purpose The metabolic syndrome (MetS) is characterized of a cluster of medical
disorders. Altered function of adipose tissue has a significant impact on whole-body …

circRNA profiling reveals an abundant circFUT10 that promotes adipocyte proliferation and inhibits adipocyte differentiation via sponging let-7

R Jiang, H Li, J Yang, X Shen, C Song, Z Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Adipose development is regulated by a series of complex processes, and non-coding RNAs
(ncRNAs), including circular RNAs (circRNAs), play important roles in regulating …

A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis

J Li, J Qi, Y Tang, H Liu, K Zhou, Z Dai, L Yuan… - Journal of …, 2021 - Springer
Our study aimed to explore the function of circRNA_0001805 in the pathogenesis of NAFLD
and the underlying mechanism. A nanodrug system (GA-RM/GZ/PL) was constructed to …

Nonalcoholic fatty liver disease (NAFLD): pathogenesis and noninvasive diagnosis

V Dorairaj, SA Sulaiman, N Abu, NA Abdul Murad - Biomedicines, 2021 - mdpi.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) or metabolic associated
fatty liver disease (MAFLD), as it is now known, has gradually increased. NAFLD is a …

Regulatory non-coding RNAs network in non-alcoholic fatty liver disease

SA Sulaiman, NIA Muhsin, R Jamal - Frontiers in Physiology, 2019 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) spectrum comprises simple steatosis and non-
alcoholic steatohepatitis (NASH) that can lead to fibrosis and cirrhosis. The patients usually …

Noncoding RNAs in nonalcoholic fatty liver disease: potential diagnosis and prognosis biomarkers

O Khalifa, K Errafii, NS Al-Akl, A Arredouani - Disease markers, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease
worldwide in part due to the concomitant obesity pandemic and insulin resistance (IR). It is …