Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …

Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …

Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

Bone marrow (BM)-mediated trained innate immunity (TII) is a state of heightened immune
responsiveness of hematopoietic stem and progenitor cells (HSPC) and their myeloid …

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder that primarily
affects the joints. One hypothesis for the pathogenesis of RA is that disease begins at …

The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Neutrophil infiltration is a hallmark of periodontitis, a prevalent oral inflammatory condition in
which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone …

Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …

The human oral cavity harbors diverse communities of microbes that live as biofilms: highly
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …