[HTML][HTML] Fatty acid β-oxidation in kidney diseases: perspectives on pathophysiological mechanisms and therapeutic opportunities

Z Gao, X Chen - Frontiers in Pharmacology, 2022 - frontiersin.org
The kidney is a highly metabolic organ and requires a large amount of ATP to maintain its
filtration-reabsorption function, and mitochondrial fatty acid β-oxidation serves as the main …

[HTML][HTML] Roles of exosomes and exosome-derived miRNAs in pulmonary fibrosis

Y Yang, H Huang, Y Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Pulmonary fibrosis is a chronic, progressive fibrosing interstitial lung disease of unknown
etiology that leads rapidly to death. It is characterized by the replacement of healthy tissue …

[HTML][HTML] Promoting vascularized bone regeneration via strontium-incorporated hydroxyapatite bioceramic

Y Zhuang, A Liu, S Jiang, U Liaqat, K Lin, W Sun… - Materials & Design, 2023 - Elsevier
Angiogenesis, well-coupled with osteogenesis, plays an indispensable and vital role in
modulating hard tissue regeneration. Thus, simultaneously promoting osteogenesis and …

Mesenchymal stem cell-derived exosomes ameliorate diabetic kidney disease through the NLRP3 signaling pathway

Y Wang, J Liu, H Wang, S Lv, Q Liu, S Li, X Yang… - Stem Cells, 2023 - academic.oup.com
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide.
Exosomes (Exo) derived from human umbilical cord mesenchymal stem cells (HUC-MSCs) …

Intravenous injection of human umbilical cord-derived mesenchymal stem cells ameliorates not only blood glucose but also nephrotic complication of diabetic rats …

X Li, L Guo, J Chen, H Liang, Y Liu, W Chen… - Stem Cell Research & …, 2023 - Springer
Background Diabetic nephropathy (DN) is one of the most severe complications of diabetes
mellitus, which is characterized by early occurrence of albuminuria and end-stage …

Adipose-derived stem cell exosomes regulate Nrf2/Keap1 in diabetic nephropathy by targeting FAM129B

P Ren, F Qian, L Fu, W He, Q He, J Jin… - Diabetology & Metabolic …, 2023 - Springer
Background Exosomes from adipose-derived stem cells (ADSCs-Exos) have exhibited a
therapeutic role in diabetic nephropathy (DN). Further studies are needed to investigate how …

Exosome proteomics reveals the deregulation of coagulation, complement and lipid metabolism proteins in gestational diabetes mellitus

EG Bernea, VI Suica, E Uyy, A Cerveanu-Hogas… - Molecules, 2022 - mdpi.com
Exosomes are small extracellular vesicles with a variable protein cargo in consonance with
cell origin and pathophysiological conditions. Gestational diabetes mellitus (GDM) is …

The role of miRNAs carried by extracellular vesicles in type 2 diabetes and its complications

Y Chao, T Gu, Z Zhang, T Wu, J Wang… - Journal of …, 2023 - Wiley Online Library
Diabetes poses severe global public health problems and places heavy burdens on the
medical and economic systems of society. Type 2 diabetes (T2D) accounts for 90% of these …

[HTML][HTML] Stem cell-derived exosomal microRNAs: potential therapies in diabetic kidney disease

H Wang, J Wang, T Liu, Y Leng, W Yang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The diabetic kidney disease (DKD) is chronic kidney disease caused by diabetes and one of
the most common comorbidities. It is often more difficult to treat end-stage renal disease …

Extracellular vesicles from urine-derived stem cell for tissue engineering and regenerative medicine

YJ Dong, JJ Hu, YT Song, YY Gao… - … Engineering Part B …, 2024 - liebertpub.com
The potential of urine-derived stem cells (USCs) for tissue engineering and regenerative
medicine has attracted much attention during the last few decades. However, it has been …