Delineating the protective action of cordycepin against cadmium induced oxidative stress and gut inflammation through downregulation of NF-κB pathway

PS Priya, R Murugan, BO Almutairi, S Arokiyaraj… - Environmental …, 2023 - Elsevier
Cadmium (Cd) exposure is known to cause gut inflammation. In this study, we investigated
the protective effects of cordycepin, a natural compound with pharmacological properties …

Enhancing cordycepin production in liquid static cultivation of Cordyceps militaris by adding vegetable oils as the secondary carbon source

J Tang, Z Qian, H Wu - Bioresource technology, 2018 - Elsevier
This study evaluated different vegetable oils as the second carbon source in liquid static
culture of Cordyceps militaris in terms of mycelial growth and cordycepin production. The …

Heat and light stresses affect metabolite production in the fruit body of the medicinal mushroom Cordyceps militaris

Z Jiaojiao, W Fen, L Kuanbo, L Qing, Y Ying… - Applied Microbiology …, 2018 - Springer
Cordyceps militaris is a highly valued edible and medicinal fungus due to its production of
various metabolites, including adenosine, cordycepin, N 6-(2-hydroxyethyl)-adenosine, and …

Cordycepin and kinase inhibition in cancer

MA Khan, M Tania - Drug Discovery Today, 2023 - Elsevier
Highlights•Kinases are important cellular enzymes but abnormally expressed in
cancer.•Kinase inhibitors are potential therapeutic agents against cancer.•Cordycepin is a …

Role of reactive oxygen species in cancer progression

D Kashyap, HS Tuli, K Sak, VK Garg, N Goel… - Current Pharmacology …, 2019 - Springer
Abstract Purpose of Review Although there are significant improvements in diagnosis and
therapeutics tools, cancer remained a major cause of deaths in developing and developed …

Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal

C Jeong, DB Witonsky, B Basnyat, M Neupane… - PLoS …, 2018 - journals.plos.org
Adaptive evolution in humans has rarely been characterized for its whole set of components,
ie selective pressure, adaptive phenotype, beneficial alleles and realized fitness differential …

[HTML][HTML] Neuroinflammation in parkinson's disease and its treatment opportunities

E Çınar, BC Tel, G Şahin - Balkan medical journal, 2022 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a complex, chronic, and progressive neurodegenerative
disease that is characterized by irreversible dopaminergic neuronal loss in the substantia …

The role of autophagy in anti-cancer and health promoting effects of cordycepin

YY Chen, CH Chen, WC Lin, CW Tung, YC Chen… - Molecules, 2021 - mdpi.com
Cordycepin is an adenosine derivative isolated from Cordyceps sinensis, which has been
used as an herbal complementary and alternative medicine with various biological activities …

Cordycepin alleviates airway hyperreactivity in a murine model of asthma by attenuating the inflammatory process

X Yang, Y Li, Y He, T Li, W Wang, J Zhang, J Wei… - International …, 2015 - Elsevier
Cordycepin (Cor), which is a naturally occurring nucleoside derivative isolated from
Cordyceps militaris, has been shown to exert excellent antiinflammatory activity in a murine …

Cordycepin induces apoptotic cell death of human brain cancer through the modulation of autophagy

N Chaicharoenaudomrung, T Jaroonwitchawan… - Toxicology in Vitro, 2018 - Elsevier
Brain cancer, in particular neuroblastoma and glioblastoma, is a global challenge to human
health. Cordycepin, extracted from Cordyceps ssp., has been revealed as a strong …