Bioactive compounds from Cordyceps and their therapeutic potential

KV Krishna, RS Ulhas, A Malaviya - Critical reviews in …, 2023 - Taylor & Francis
The Clavicipitaceae family's largest and most diverse genus is Cordyceps. They are most
abundant and diverse in humid temperate and tropical forests and have a wide distribution …

Delineating the protective action of cordycepin against cadmium induced oxidative stress and gut inflammation through downregulation of NF-κB pathway

PS Priya, R Murugan, BO Almutairi, S Arokiyaraj… - Environmental …, 2023 - Elsevier
Cadmium (Cd) exposure is known to cause gut inflammation. In this study, we investigated
the protective effects of cordycepin, a natural compound with pharmacological properties …

Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosis

HH Lee, S Lee, K Lee, YS Shin, H Kang… - DARU Journal of …, 2015 - Springer
Background Cordyceps militaris has been used as a traditional medicine in Asian countries
for a long time. Different types of Cordyceps extract were reported to have various …

Comparison of Major Bioactive Compounds of the Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Fruiting Bodies Cultured on Wheat Substrate …

M Guo, S Guo, Y Huaijun, N Bu… - International journal of …, 2016 - dl.begellhouse.com
In this study, the main bioactive compounds of the fruit bodies of Cordyceps militaris− such
as adenosine, cordycepin, polysaccharides, mannitol, superoxide dismutase (SOD), and …

Cordycepin induces apoptosis in human bladder cancer cells via activation of A3 adenosine receptors

HL Cao, ZJ Liu, Z Chang - Tumor Biology, 2017 - journals.sagepub.com
Bladder cancer is a neoplasm originated from bladder epithelial cells. The therapy for
bladder cancer is so far not satisfactory. In this study, we examined the effects of Cordyceps …

Cordycepin induces apoptosis and inhibits proliferation of human lung cancer cell line H1975 via inhibiting the phosphorylation of EGFR

Z Wang, X Wu, YN Liang, L Wang, ZX Song, JL Liu… - Molecules, 2016 - mdpi.com
Cordycepin is an active component of the traditional Chinese medicine Cordyceps sinensis
and Cordyceps militaris with notable anticancer activity. Though the prominent inhibitory …

[HTML][HTML] Neuroinflammation in parkinson's disease and its treatment opportunities

E Çınar, BC Tel, G Şahin - Balkan medical journal, 2022 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a complex, chronic, and progressive neurodegenerative
disease that is characterized by irreversible dopaminergic neuronal loss in the substantia …

Cordyceps mushroom with increased cordycepin content by the cultivation on edible insects

A Turk, MAA Abdelhamid, SW Yeon, SH Ryu… - Frontiers in …, 2022 - frontiersin.org
Cordycepin is the major constituent of Cordyceps mushroom (or Cordyceps militaris) with
therapeutic potential. Insects are the direct sources of nutrients for Cordyceps in nature …

Cordycepin down-regulates multiple drug resistant (MDR)/HIF-1α through regulating AMPK/mTORC1 signaling in GBC-SD gallbladder cancer cells

WD Wu, ZM Hu, MJ Shang, DJ Zhao… - International journal of …, 2014 - mdpi.com
Gallbladder cancer is the most common malignancy of the bile duct, with low 5-year survival
rate and poor prognosis. Novel effective treatments are urgently needed for the therapy of …

Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes

X Zhang, Q Hu, Q Weng - RSC advances, 2019 - pubs.rsc.org
Both Isaria cicadae and Isaria tenuipes are important entomopathogenic fungi used in
health foods and traditional herbal medicines in East Asia. However, the safety concerns for …