Antimicrobial, antioxidant, anti-inflammatory, and cytotoxic activities of Cordyceps militaris spent substrate

D Zhang, Q Tang, X He, Y Wang, G Zhu, L Yu - Plos one, 2023 - journals.plos.org
Cordyceps militaris is a medicinal mushroom and has been extensively used as a traditional
medicine in East Asia. After the chrysalis seeds are matured and harvested, the spent …

Metabolomic profiling reveals enrichment of cordycepin in senescence process of Cordyceps militaris fruit bodies

J Oh, DH Yoon, B Shrestha, HK Choi, GH Sung - Journal of Microbiology, 2019 - Springer
Cordyceps militaris is a species of Cordyceps that is classified in the Cordycipitaceae family
and is well known in East Asia as a traditional medicinal mushroom. Its artificial fruit body …

Anti-influenza effect of Cordyceps militaris through immunomodulation in a DBA/2 mouse model

HH Lee, H Park, GH Sung, K Lee, T Lee, I Lee… - Journal of …, 2014 - Springer
The immune-modulatory as well as anti-influenza effects of Cordyceps extract were
investigated using a DBA/2 mouse model. Three different concentrations of Cordyceps …

Natural Product Cordycepin (CD) Inhibition for NRP1/CD304 Expression and Possibly SARS-CoV-2 Susceptibility Prevention on Cancers

T Li, N Luo, J Fu, J Du, Z Liu, Q Tan, M Zheng, J He… - Microorganisms, 2023 - mdpi.com
NRP1/CD304 is a typical membrane-bound co-receptor for the vascular endothelial cell
growth factor (VEGF), semaphorin family members, and viral SARS-CoV-2. Cordycepin (CD) …

Cordycepin enhances radiosensitivity in oral squamous carcinoma cells by inducing autophagy and apoptosis through cell cycle arrest

SY Ho, WS Wu, LC Lin, YH Wu, HW Chiu… - International journal of …, 2019 - mdpi.com
Oral squamous cell carcinoma (OSCC) is one of the most common cancers worldwide and
accounts for over 90% of malignant neoplasms of the oral cavity, with a 5-year survival rate …

A new cerebroside from the entomopathogenic fungus Ophiocordyceps longiissima: Structural-electronic and antioxidant relations. Experimental and DFT calculated …

AI Elshamy, T Yoneyama, N Van Trang, NT Son… - Journal of Molecular …, 2020 - Elsevier
The chemical characterization of n-butanol soluble extract of the fungus Ophiocordyceps
longiissima NBRC 106965 afforded a new cerebroside, 1-O-(β-d-glucopyranosyl)-(2S, 3R …

Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma

X Zhou, Y Li, C Yang, D Chen, T Wang, T Liu, W Yan… - Life Sciences, 2023 - Elsevier
Cholangiocarcinoma (CCA) with a high malignancy is usually diagnosed as advanced and
is prone to metastasis and leads to a poor prognosis. It is reported that cordycepin has anti …

Cordycepin Inhibits Enterovirus A71 Replication and Protects Host Cell from Virus-Induced Cytotoxicity through Adenosine Action Pathway

YP Lee, CK Yu, TW Wong, LC Chen, BM Huang - Viruses, 2024 - mdpi.com
Enterovirus A71 (EV-A71) infection typically causes mild illnesses, such as hand-foot-and-
mouth disease (HFMD), but occasionally leads to severe or fatal neurological complications …

Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells

SM Chou, WJ Lai, TW Hong, JY Lai, SH Tsai, YH Chen… - Phytomedicine, 2014 - Elsevier
Cordyceps militaris is a well-known Chinese traditional medicinal mushroom frequently
used for tonics and recently of a potential interest for cancer intervention. Here, we explored …

Preparation, spectroscopy and molecular modelling studies of the inclusion complex of cordycepin with cyclodextrins

JQ Zhang, D Wu, KM Jiang, D Zhang, X Zheng… - Carbohydrate …, 2015 - Elsevier
The inclusion complexes of cordycepin with cyclodextrins (CDs) were prepared, the
resultant complexes were characterised by UV–vis, FTIR, DSC, SEM, XRD, ESI-MS and …