[HTML][HTML] T cells in health and disease

L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

[HTML][HTML] Cancer vaccines: Building a bridge over troubled waters

MLC Sellars, CJ Wu, EF Fritsch - Cell, 2022 - cell.com
Cancer vaccines aim to direct the immune system to eradicate cancer cells. Here we review
the essential immunologic concepts underpinning natural immunity and highlight the …

[HTML][HTML] Progress and prospect of immunotherapy for triple-negative breast cancer

C Luo, P Wang, S He, J Zhu, Y Shi, J Wang - Frontiers in Oncology, 2022 - frontiersin.org
Breast cancer is the most commonly diagnosed cancer (estimated 2.3 million new cases in
2020) and the leading cause of cancer death (estimated 685,000 deaths in 2020) in women …

[HTML][HTML] Neoantigens: promising targets for cancer therapy

N Xie, G Shen, W Gao, Z Huang, C Huang… - Signal transduction and …, 2023 - nature.com
Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …

[HTML][HTML] Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?

MH Kazemi, M Sadri, A Najafi, A Rahimi… - Frontiers in …, 2022 - frontiersin.org
Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are
recruited into the tumor site to fight against tumors. However, their small number and …

[HTML][HTML] The screening, identification, design and clinical application of tumor-specific neoantigens for TCR-T cells

J Li, Z Xiao, D Wang, L Jia, S Nie, X Zeng, W Hu - Molecular Cancer, 2023 - Springer
Recent advances in neoantigen research have accelerated the development of tumor
immunotherapies, including adoptive cell therapies (ACTs), cancer vaccines and antibody …

Tumor-infiltrating lymphocyte therapy in melanoma: facts to the future

A Betof Warner, PG Corrie, O Hamid - Clinical Cancer Research, 2023 - AACR
Adoptive cell therapy with tumor-infiltrating lymphocytes (TIL) is gaining momentum and
demonstrating durable responses in patients with advanced melanoma. Although …

[HTML][HTML] Engineering induced pluripotent stem cells for cancer immunotherapy

Y Zhou, M Li, K Zhou, J Brown, T Tsao, X Cen… - Cancers, 2022 - mdpi.com
Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

[HTML][HTML] Emerging trends in immunotherapy for cancer

AK Mishra, A Ali, S Dutta, S Banday, SK Malonia - Diseases, 2022 - mdpi.com
Recent advances in cancer immunology have enabled the discovery of promising
immunotherapies for various malignancies that have shifted the cancer treatment paradigm …

[HTML][HTML] Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - … and Targeted Therapy, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …