Pulmonary aspects of COVID-19

KC Doerschug, GA Schmidt - Annual review of medicine, 2022 - annualreviews.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory virus that
gains entry via angiotensin-converting enzyme 2 (ACE2) within airway epithelium. Patients …

[HTML][HTML] Sulfated liposome-based artificial cell membrane glycocalyx nanodecoys for coronavirus inactivation by membrane fusion

X Li, N Cheng, D Shi, Y Li, C Li, M Zhu, Q Jin, Z Wu… - Bioactive Materials, 2024 - Elsevier
As a broad-spectrum antiviral nanoparticle, the cell membrane nanodecoy is a promising
strategy for preventing viral infections. However, most of the cell membrane nanodecoys can …

[HTML][HTML] SARS-CoV-2 vaccination elicits broad and potent antibody effector functions to variants of concern in vulnerable populations

AP Hederman, H Natarajan, L Heyndrickx… - Nature …, 2023 - nature.com
SARS-CoV-2 variants have continuously emerged in the face of effective vaccines. Reduced
neutralization against variants raises questions as to whether other antibody functions are …

Dendritic Cell‐Mediated Cross‐Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS‐CoV‐2

R Lázaro‐Gorines, P Pérez, I Heras‐Murillo… - Advanced …, 2023 - Wiley Online Library
Administration of neutralizing antibodies (nAbs) has proved to be effective by providing
immediate protection against SARS‐CoV‐2. However, dual strategies combining virus …

A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern

D Wu, J Cong, J Wei, J Hu, W Sun, W Ran… - International Journal …, 2023 - Taylor & Francis
Background The emergence of the coronavirus disease 2019 (COVID-19) pandemic and the
new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern …

Design of a bifunctional pan-sarbecovirus entry inhibitor targeting the cell receptor and viral fusion protein

H Jin, L Cheng, Y Gong, Y Zhu, H Chong… - Journal of …, 2023 - Am Soc Microbiol
Development of highly effective antivirals that are robust to viral evolution is a practical
strategy for combating the continuously evolved severe acute respiratory syndrome …

Safety and immunogenicity of inactivated COVID-19 vaccination in adult rheumatic patients in South China: a prospective study

H Zeng, H Liu, Z Liu, X Zhou, X Lu, Z Yan… - Human Vaccines & …, 2022 - Taylor & Francis
Patients with rheumatic diseases (RD) are considered to be a high-risk population for
infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The …

Characterization of a neutralizing antibody that recognizes a loop region adjacent to the receptor-binding interface of the SARS-CoV-2 spike receptor-binding domain

I Anzai, J Fujita, C Ono, Y Kosaka… - Microbiology …, 2024 - Am Soc Microbiol
Although the global crisis caused by the coronavirus disease 2019 (COVID-19) pandemic is
over, the global epidemic of the disease continues. Severe acute respiratory syndrome …

[HTML][HTML] Production of two SARS-CoV-2 neutralizing antibodies with different potencies in Nicotiana benthamiana

R Frigerio, C Marusic, ME Villani, C Lico… - Frontiers in Plant …, 2022 - frontiersin.org
Monoclonal antibodies are considered to be highly effective therapeutic tools for the
treatment of mild to moderate COVID-19 patients. In the present work, we describe the …

[HTML][HTML] Neutralization of the new coronavirus by extracting their spikes using engineered liposomes

Z Zhang, MR King - Nanomedicine: Nanotechnology, Biology and Medicine, 2023 - Elsevier
The devastating COVID-19 pandemic motivates the development of safe and effective
antivirals to reduce morbidity and mortality associated with infection. We developed …