The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
In 2019–2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent
of a several acute respiratory infection named COVID-19, which is causing a worldwide …

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …

Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19

Y Yang, C Shen, J Li, J Yuan, J Wei, F Huang… - Journal of Allergy and …, 2020 - Elsevier
Background The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 was first reported in Wuhan, December 2019, and …

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

Y Liu, Y Yang, C Zhang, F Huang, F Wang… - Science China Life …, 2020 - Springer
The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan, Hubei
province, and rapidly spread to many provinces in China as well as other countries. Here we …

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

Y Xiong, Y Liu, L Cao, D Wang, M Guo… - Emerging microbes & …, 2020 - Taylor & Francis
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak
has caused devastating mortality and posed a great threat to public health. However, efforts …

The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

[PDF][PDF] Lessons for COVID-19 immunity from other coronavirus infections

A Sariol, S Perlman - Immunity, 2020 - cell.com
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China

R Chen, L Sang, M Jiang, Z Yang, N Jia, W Fu… - Journal of Allergy and …, 2020 - Elsevier
Background Crucial roles of hematologic and immunologic responses in progression of
coronavirus disease 2019 (COVID-19) remain largely unclear. Objective We sought to …