In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …

Injectable drug nanocarriers have greatly benefited in their clinical development from the
addition of a superficial hydrophilic corona to improve their cargo pharmacokinetics. The …

With the rapid development of nanotechnology, nanoparticles have been widely used in
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …

Although the concept of selective delivery has been postulated over 100 years ago, no
targeted nanomedicine has been clinically approved so far. Nanoparticles modified with …

Most therapeutic agents suffer from poor solubility, rapid clearance from the blood stream, a
lack of targeting, and often poor translocation ability across cell membranes. Drug/gene …

“All-in-one” carrier-free-based nano-multi-drug self-delivery system could combine triple
advantages of small molecules, nanoscale characteristics, and synergistic combination …

Nanoparticles covered with ligand shells comprising both positively and negatively charged
ligands exhibit Gram‐selective antibacterial action controlled by a single experimental …

Understanding how influenza viruses traverse the mucus and recognize host cells is critical
for evaluating their zoonotic potential, and for prevention and treatment of the disease. The …

Carrier-free nanodrug with exceptionally high drug payload has attracted increasing
attentions. Herein, we construct a pH/ROS cascade-responsive nanodrug which could …

Targeted drug delivery critically depends on the binding selectivity of cargo-transporting
colloidal particles. Extensive theoretical work has shown that two factors are necessary to …