Vancomycin Loaded Amino-Functionalized MCM-48 Mesoporous Silica Nanoparticles as a Promising Drug Carrier in Bone Substitutes for Bacterial Infection …

SN Rahaman, S Pathmanapan, A Sidharthan… - Applied Biochemistry …, 2023 - Springer
Orthopedic infections due to biofilm formation in biomaterial-based implants have become
challenging in bone tissue engineering. In the present study, in vitro antibacterial analysis of …

Analysis of the Ability of Different Allografts to Act as Carrier Grafts for Local Drug Delivery

N Bormann, A Schmock, A Hanke, V Eras… - Journal of Functional …, 2023 - mdpi.com
Bone defects and infections pose significant challenges for treatment, requiring a
comprehensive approach for prevention and treatment. Thus, this study sought to evaluate …

Drug Delivery Systems for Tissue Engineering

PA Tărăbuță, L Motelica, D Ficai, O Oprea… - Biomaterials and Tissue …, 2023 - Springer
Drug delivery systems (DDSs) are developed having in view the need to control the dose
(within the therapeutic level) and the time of administration of different biologically active …

Struggling with a cefazolin impregnation protocol of bone chips

K Dendoncker, G Putzeys, T Nieuwenhuizen, P Voet… - 2023 - researchsquare.com
Antibiotics released locally through a carrier is a commonly used technique to prevent
infection in orthopaedic procedures. Antibiotic-impregnated bone chips are an interesting …

[PDF][PDF] Arthrodesis following persistent periprosthetic knee infection using femoral condyle allograft: a case report and review of literature

GV Pinto, NM Luís, JR Cabral, M Vale… - … Journal of Research …, 2024 - researchgate.net
Periprosthetic joint infections (PJI) of the knee are difficult to treat and can require costly and
prolonged hospital stays, weeks or months of antibiotic therapy, and multiple surgical …