New insights into the role of the complement system in human viral diseases

E Ostrycharz, B Hukowska-Szematowicz - Biomolecules, 2022 - mdpi.com
The complement system (CS) is part of the human immune system, consisting of more than
30 proteins that play a vital role in the protection against various pathogens and diseases …

Deep Learning‐Enabled Multiplexed Point‐of‐Care Sensor using a Paper‐Based Fluorescence Vertical Flow Assay

A Goncharov, HA Joung, R Ghosh, GR Han, ZS Ballard… - Small, 2023 - Wiley Online Library
Multiplexed computational sensing with a point‐of‐care serodiagnosis assay to
simultaneously quantify three biomarkers of acute cardiac injury is demonstrated. This point …

Antiviral potential of algal metabolites—a comprehensive review

A Pagarete, AS Ramos, P Puntervoll, MJ Allen… - Marine Drugs, 2021 - mdpi.com
Historically, algae have stimulated significant economic interest particularly as a source of
fertilizers, feeds, foods and pharmaceutical precursors. However, there is increasing interest …

Zoonoses and global epidemics

SD Judson, PM Rabinowitz - Current Opinion in Infectious …, 2021 - journals.lww.com
Zoonoses and global epidemics : Current Opinion in Infectious Diseases Zoonoses and
global epidemics : Current Opinion in Infectious Diseases Log in or Register Subscribe to …

Emergence of infectious diseases and role of advanced nanomaterials in point-of-care diagnostics: a review

K Markandan, YW Tiong, R Sankaran… - Biotechnology and …, 2022 - Taylor & Francis
Infectious outbreaks are the foremost global public health concern, challenging the current
healthcare system, which claims millions of lives annually. The most crucial way to control …

[HTML][HTML] A review of broadly protective monoclonal antibodies to treat Ebola virus disease

P Rijal, FR Donnellan - Current Opinion in Virology, 2023 - Elsevier
Highlights•mAbs mixture targeting independent epitopes are better therapeutics.•Optimizing
antibody efficacy: in vitro maturation, afucosylation, Fc modifications.•Monitoring of natural …

Safety and immunogenicity of the two-dose heterologous Ad26. ZEBOV and MVA-BN-Filo Ebola vaccine regimen in infants: a phase 2, randomised, double-blind …

EML Choi, B Lacarra, MO Afolabi, BM Ale… - The Lancet Global …, 2023 - thelancet.com
Background This study assessed the safety and immunogenicity of the Ad26. ZEBOV and
MVA-BN-Filo Ebola virus (EBOV) vaccine regimen in infants aged 4–11 months in Guinea …

Crosstalk between RNA viruses and DNA sensors: Role of the cGAS‐STING signalling pathway

YM Fan, YL Zhang, H Luo… - Reviews in medical …, 2022 - Wiley Online Library
Despite only comprising half of all known viral species, RNA viruses are disproportionately
responsible for many of the worst epidemics in human history, including outbreaks of …

A review: The antiviral activity of cyclic peptides

LY Chia, PV Kumar, MAA Maki, G Ravichandran… - International Journal of …, 2022 - Springer
In the design and development of therapeutic agents, macromolecules with restricted
structures have stronger competitive edges than linear biological entities since cyclization …

Field performance of three Ebola rapid diagnostic tests used during the 2018–20 outbreak in the eastern Democratic Republic of the Congo: a retrospective …

D Mukadi-Bamuleka, J Bulabula-Penge… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The Democratic Republic of the Congo has confronted 13 outbreaks
of Ebola virus disease since 1976. Rapid diagnostic tests (RDTs) detecting viral antigens …