HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases
W Ren, L Zhao, Y Sun, X Wang, X Shi - Molecular Medicine, 2023 - Springer
HMGB1, a nucleoprotein, is expressed in almost all eukaryotic cells. During cell activation
and cell death, HMGB1 can function as an alarm protein (alarmin) or damage-associated …
and cell death, HMGB1 can function as an alarm protein (alarmin) or damage-associated …
[HTML][HTML] NLRP3 inflammasome and its role in autoimmune diseases: A promising therapeutic target
W Ren, Y Sun, L Zhao, X Shi - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines IL-1β and …
innate immune responses by activating caspase-1 and the inflammatory cytokines IL-1β and …
Quercetin alleviates DEHP exposure-induced pyroptosis and cytokine expression changes in grass carp L8824 cell line by inhibiting ROS/MAPK/NF-κB pathway
H Cai, K Li, Y Yin, X Ni, S Xu - Fish & Shellfish Immunology, 2023 - Elsevier
Abstract Bis (2-ethylhexyl) phthalate (DEHP) is not only a widely used plasticizer but also a
common endocrine disruptor that frequently lingers in water, posing a threat to the health of …
common endocrine disruptor that frequently lingers in water, posing a threat to the health of …
Elucidating the role of Pyroptosis in papillary thyroid cancer: prognostic, immunological, and therapeutic perspectives
F Li, R Du, J Kou, J Li, L Zhou, D Zhang, Y Fu… - Cancer Cell …, 2024 - Springer
Background Pyroptosis, an inflammatory form of programmed cell death, has been
implicated in the pathogenesis and progression of several cancers. However, the …
implicated in the pathogenesis and progression of several cancers. However, the …
Giardia VSPAS7 protein attenuates Giardia intestinalis-induced host macrophage pyroptosis
M Sun, Z Zhao, Y Li, L Cao, J Li, X Zhang, X Li… - Parasites & …, 2023 - Springer
Background The unicellular protozoan parasite Giardia intestinalis, which primarily infects
humans and animals such as cattle and sheep, is having a major negative impact on public …
humans and animals such as cattle and sheep, is having a major negative impact on public …
重组日本血吸虫半胱氨酸蛋白酶抑制剂对小鼠急性肝衰竭相关急性肾损伤的保护作用
薛媛， 杨小迪， 张华平， 张婷婷， 陈伟豪， 常欣悦… - 中国血吸虫病防治 …, 2023 - zgxfzz.com
目的探究重组日本血吸虫半胱氨酸蛋白酶抑制剂(rSj⁃ Cys) 对急性肝衰竭所致急性肾损伤的
保护作用及其机制, 为急性肾损伤临床治疗提供科学依据. 方法将24 只雄性C57BL/6J 小鼠(6~ 8 …
保护作用及其机制, 为急性肾损伤临床治疗提供科学依据. 方法将24 只雄性C57BL/6J 小鼠(6~ 8 …
Protective effect of recombinant Schistosoma japonicum cystatin against acute kidney injury associated with acute liver failure in mice
XUE Yuan, Y Xiaodi, Z Huaping, Z Tingting… - Chinese Journal of …, 2023 - zgxfzz.com
Objective To evaluate the protective effect of recombinant Schistosoma japonicum cystatin
(rSj⁃ Cys) against acute kidney injury induced by acute liver failure and unravel the …
(rSj⁃ Cys) against acute kidney injury induced by acute liver failure and unravel the …