Protective roles and protective mechanisms of neutralizing antibodies against SARS-CoV-2 infection and their potential clinical implications

EC Abebe, TA Dejenie - Frontiers in Immunology, 2023 - frontiersin.org
Neutralizing antibodies (NAbs) are central players in the humoral immunity that defends the
body from SARS-CoV-2 infection by blocking viral entry into host cells and neutralizing their …

SARS-CoV-2: immunity, challenges with current vaccines, and a novel perspective on mucosal vaccines

R Sunagar, A Singh, S Kumar - Vaccines, 2023 - mdpi.com
The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …

Electrochemical immunoassay for the detection of SARS-CoV-2 nucleocapsid protein in nasopharyngeal samples

IC Samper, CJ McMahon, MS Schenkel… - Analytical …, 2022 - ACS Publications
Point-of-care (POC) methods currently available for detecting SARS-CoV-2 infections still
lack accuracy. Here, we report the development of a highly sensitive electrochemical …

A comprehensive review on immunogen and immune-response proteins of SARS-CoV-2 and their applications in prevention, diagnosis, and treatment of COVID-19

D Zhang, D Kukkar, KH Kim, P Bhatt - International Journal of Biological …, 2024 - Elsevier
Exposure to severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2) prompts
humoral immune responses in the human body. As the auxiliary diagnosis of a current …

Endogenous antibody responses to SARS-CoV-2 in patients with mild or moderate COVID-19 who received bamlanivimab alone or bamlanivimab and etesevimab …

L Zhang, J Poorbaugh, M Dougan, P Chen… - Frontiers in …, 2021 - frontiersin.org
Background Neutralizing monoclonal antibodies (mAbs) to SARS-CoV-2 are clinically
efficacious when administered early, decreasing hospitalization and mortality in patients …

COVID-19 patients exhibit unique transcriptional signatures indicative of disease severity

AR Daamen, P Bachali, CA Bonham… - Frontiers in …, 2022 - frontiersin.org
COVID-19 manifests a spectrum of respiratory symptoms, with the more severe often
requiring hospitalization. To identify markers for disease progression, we analyzed …

Enhanced SARS-CoV-2 IgG durability following COVID-19 mRNA booster vaccination and comparison of BNT162b2 with mRNA-1273

SM Ailsworth, B Keshavarz, NE Richards… - Annals of Allergy …, 2023 - Elsevier
Abstract Background BNT162b2 (Pfizer/BioNTech, Comirnaty) and mRNA-1273 (Moderna,
Spikevax) are messenger RNA (mRNA) vaccines that elicit antibodies against the severe …

The SARS-CoV-2 antibodies, their diagnostic utility, and their potential for vaccine development

K Hajissa, A Mussa, MI Karobari, MA Abbas, IK Ibrahim… - Vaccines, 2022 - mdpi.com
Antibodies (Abs) are important immune mediators and powerful diagnostic markers in a
wide range of infectious diseases. Understanding the humoral immunity or the development …

Detection of neutralizing antibodies against SARS-CoV-2 post-vaccination in health care workers of a large tertiary hospital in spain by using a rapid test LFIC and …

J Tuells, M Parra-Grande, FJ Santos-Calle… - Vaccines, 2022 - mdpi.com
The presence of neutralizing antibodies (NAbs) against SARS-CoV-2 represent a surrogate
marker of immunologic protection in populations at high risk of infection such as healthcare …

Anti-S antibodies against SARS-CoV-2 infection among four types of vaccines in Malaysia

NA Lodz, NF Mat Tamizi… - Asia Pacific Journal …, 2024 - journals.sagepub.com
Monitoring SARS-CoV-2 antibody levels can provide insights into a person's immunity to
COVID-19 and inform decisions about vaccination and public health measures. Anti-S may …