Elucidation of inhibitor-binding pockets of D-amino acid oxidase using docking simulation and N-sulfanylethylanilide-based labeling technology
T Kohiki, Y Kato, Y Nishikawa, K Yorita… - Organic & …, 2017 - pubs.rsc.org
Because of the relevance of D-serine (D-Ser) to schizophrenia, inhibitors of D-amino acid
oxidase (DAO), which catalyzes degradation of D-Ser in the presence of flavin adenine …
oxidase (DAO), which catalyzes degradation of D-Ser in the presence of flavin adenine …
Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids
Y Kato, N Hin, N Maita, AG Thomas, S Kurosawa… - European Journal of …, 2018 - Elsevier
A series of thiophene-2-carboxylic acids and thiophene-3-carboxylic acids were identified as
a new class of DAO inhibitors. Structure-activity relationship (SAR) studies revealed that …
a new class of DAO inhibitors. Structure-activity relationship (SAR) studies revealed that …