Antimicrobial activity of curcumin in nanoformulations: A comprehensive review

JK Trigo-Gutierrez, Y Vega-Chacón, AB Soares… - International journal of …, 2021 - mdpi.com
Curcumin (CUR) is a natural substance extracted from turmeric that has antimicrobial
properties. Due to its ability to absorb light in the blue spectrum, CUR is also used as a …

Are nutraceuticals effective in COVID-19 and post-COVID prevention and treatment?

A Catalano, D Iacopetta, J Ceramella, ACD Maio… - Foods, 2022 - mdpi.com
The beginning of the end or the end of the beginning? After two years mastered by
coronavirus disease 19 (COVID-19) pandemic, we are now witnessing a turnaround. The …

Kobophenol A inhibits binding of host ACE2 receptor with spike RBD domain of SARS-CoV-2, a lead compound for blocking COVID-19

S Gangadevi, VN Badavath, A Thakur… - The journal of …, 2021 - ACS Publications
In the search for inhibitors of COVID-19, we have targeted the interaction between the
human angiotensin-converting enzyme 2 (ACE2) receptor and the spike receptor binding …

Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions

A Goc, W Sumera, M Rath, A Niedzwiecki - PLoS One, 2021 - journals.plos.org
In the pursuit of suitable and effective solutions to SARS-CoV-2 infection, we investigated
the efficacy of several phenolic compounds in controlling key cellular mechanisms involved …

The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials

SO Oselusi, P Dube, AI Odugbemi, KA Akinyede… - Computers in biology …, 2024 - Elsevier
Antimicrobial resistance (AMR) has become more of a concern in recent decades,
particularly in infections associated with global public health threats. The development of …

Understanding the driving forces that trigger mutations in SARS-CoV-2: mutational energetics and the role of arginine blockers in COVID-19 therapy

H Ridgway, CT Chasapis, K Kelaidonis, I Ligielli… - Viruses, 2022 - mdpi.com
SARS-CoV-2 is a global challenge due to its ability to mutate into variants that spread more
rapidly than the wild-type virus. Because the molecular biology of this virus has been studied …

Discovery of multitarget inhibitors against insect chitinolytic enzymes via machine learning-based virtual screening

Y Ding, S Chen, H Liu, T Liu… - Journal of Agricultural and …, 2023 - ACS Publications
Multitarget inhibitors of insect chitinolytic enzymes are promising sources of green
insecticides. Machine learning (ML) is an emerging virtual screening method that can …

Screening S protein–ACE2 blockers from natural products: strategies and advances in the discovery of potential inhibitors of COVID-19

H Liu, X Liu, X Yuan, C Xu, F Wang, J Lin, R Xu… - European Journal of …, 2021 - Elsevier
Abstract The Coronavirus disease, 2019 (COVID-19) is caused by severe acute respiratory
syndrome Coronavirus 2 (SARS-CoV-2), which poses a major threat to human life and …

Molecular docking and molecular dynamics simulations discover curcumin analogue as a plausible dual inhibitor for SARS-CoV-2

S Rampogu, G Lee, JS Park, KW Lee… - International Journal of …, 2022 - mdpi.com
Recently, the world has been witnessing a global pandemic with no effective therapeutics
yet, while cancer continues to be a major disease claiming many lives. The natural …

[HTML][HTML] Herbal medications and natural products for patients with covid-19 and diabetes mellitus: Potentials and challenges

AP Yusuf, J Zhang, J Li, A Muhammad, MB Abubakar - Phytomedicine plus, 2022 - Elsevier
Background The presence of diabetes mellitus (DM) among COVID-19 patients is
associated with increased hospitalization, morbidity, and mortality. Evidence has shown that …