Human studies consistently identify bioenergetic maladaptations in brains upon aging and
neurodegenerative disorders of aging (NDAs), such as Alzheimer's disease, Parkinson's …

In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

Alzheimer's disease (AD) is a progressive neurological disorder that affects the central
nervous system (CNS), leading to memory and cognitive decline. In AD, the brain …

Aging is a ubiquitous biological process that limits the maximal lifespan of most organisms.
Significant efforts by many groups have identified mechanisms that, when triggered by …

Alzheimer's Disease (AD) remains a formidable challenge due to its complex pathology,
notably involving mitochondrial dysfunction and dysregulated microRNA (miRNA) signaling …

Epigenetic aging clocks are computational models that predict age using DNA methylation
information. Initially, first-generation clocks were developed to make predictions using CpGs …

Background: Although sporadic Alzheimer's disease (AD) is a neurodegenerative disorder
of unknown etiology, familial AD is associated with specific gene mutations. A commonality …

Objective Postoperative delirium (POD) is a common postoperative complication in elderly
patients, especially those undergoing cardiac surgery, which seriously affects the short-and …

A common neurodegenerative disease, Alzheimer Disease (AD) affects society. Early
intervention and personalized care require accurate condition prediction. A hybrid model …

Epigenetic aging clocks are computational models that use DNA methylation sites to predict
age. Since cheek swabs are non-invasive and painless, collecting DNA from buccal tissue is …