Adrenal incidentalomas are adrenal masses detected on imaging performed for reasons
other than suspected adrenal disease. In most cases, adrenal incidentalomas are …

Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …

Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

Importance Primary aldosteronism (PA) is a common cause of secondary hypertension and
an independent risk factor for cardiovascular morbidity and mortality. Fewer than 2% to 4 …

Aldosterone and cortisol serve important roles in the pathogenesis of cardiovascular
diseases and metabolic disorders. Epigenetics is a mechanism to control enzyme …

Angiotensin II, a major culprit in cardiovascular disease, activates mediators that are also
involved in pathological cardiac remodeling. In this context, we aimed at investigating the …

Objective Primary aldosteronism (PA) is one of the most frequent causes of secondary
hypertension. Although clinical practice guidelines recommend a diagnostic process, details …

Background: Salt sensitivity of blood pressure (SSBP) is a trait observed in both humans and
animals, characterized by an increase in blood pressure (BP) following salt loading or a …

Introduction Cardiovascular mortality is significantly higher in patients with primary
hyperparathyroidism (PHPT) compared to the general population. The role of the renin …

BACKGROUND: Disease-causing mutations in CACNA1D gene occur in aldosterone-
producing adenomas and familial hyperaldosteronism. We determined whether single …