[HTML][HTML] Next-generation treatments: Immunotherapy and advanced therapies for COVID-19

JA Arevalo-Romero, SM Chingaté-López, BA Camacho… - Heliyon, 2024 - cell.com
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), emerged in 2019 following prior outbreaks of coronaviruses like SARS and …

Understanding Mucosal Physiology and Rationale of Formulation Design for Improved Mucosal Immunity

M Biswas, M Nurunnabi, Z Khatun - ACS Applied Bio Materials, 2024 - ACS Publications
The oral and nasal cavities serve as critical gateways for infectious pathogens, with
microorganisms primarily gaining entry through these routes. Our first line of defense against …

Humoral immunogenicity assessment after receiving three types of SARS-CoV-2 vaccine

N Najafi, H Soleimanjahi, L Moghaddam-Banaem… - Scientific Reports, 2023 - nature.com
Several vaccines have been developed against SARS-CoV-2 and subsequently approved
by national/international regulators. Detecting specific antibodies after vaccination enables …

Mucosal SARS-CoV-2 vaccination of rodents elicits superior systemic T central memory function and cross-neutralising antibodies against variants of concern

A O'Neill, CK Mantri, CW Tan, WAA Saron… - Ebiomedicine, 2024 - thelancet.com
Background COVID-19 vaccines used in humans are highly effective in limiting disease and
death caused by the SARS-CoV-2 virus, yet improved vaccines that provide greater …

[HTML][HTML] Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein …

G Sarnelli, A Del Re, I Palenca, SB Franzin, J Lu… - Biomedicine & …, 2024 - Elsevier
While current anti-Spike protein (SP) vaccines have been pivotal in managing the pandemic,
their limitations in delivery, storage, and the inability to provide mucosal immunization …

An Observational Prospective Cohort Study of Vaccine Effectiveness Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection of an Aerosolized, Inhaled …

FZ Wang, CH Zhang, L Tang… - The Journal of …, 2024 - academic.oup.com
Using a prospective, observational cohort study during the post–“dynamic COVID-zero”
wave in China, we estimated short-term relative effectiveness against Omicron BA. 5 …

Safety, immunogenicity, and protective effective of inhaled COVID‐19 vaccines: A systematic review and meta‐analysis

G Song, R Li, M Cheng - Journal of Medical Virology, 2024 - Wiley Online Library
This study aimed to examine the safety, immunogenicity and protective effective of inhaled
COVID‐19 vaccines (ICVs). Literature research was done through EMBASE, Cochrane …

[图书][B] Immune responses after SARS-CoV-2 infection and/or vaccination

S Havervall - 2024 - openarchive.ki.se
From the start of the COVID-19 pandemic, it was clear that studying immune responses after
SARS-CoV-2 infection and later on, after vaccination, was of outmost importance in battling …

Why Should Vaccines against Respiratory Diseases Go Mucosal? B Cell Epitope-Based Vaccines against SARS-CoV-2

J Tobias, P Steinberger, J Wilkinson, G Klais, M Kundi… - 2024 - preprints.org
Immunity against respiratory pathogens is often short-term, and consequently there is an
unmet need for effective prevention of such infections. One such infectious disease is COVID …