[HTML][HTML] Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology

F Zhu, W Li, L Wang, B Dai, Z Liu, H Wu… - Journal of Orthopaedic …, 2023 - Springer
Abstract Background Liuwei Dihuang Pill (LP) was verified to alleviate postmenopausal
osteoporosis (PMOP) development. Nevertheless, the major constituent of LP and the …

[HTML][HTML] Targeting bone homeostasis regulation: potential of traditional Chinese medicine flavonoids in the treatment of osteoporosis

J Du, Y Wang, C Wu, X Zhang, X Zhang… - Frontiers in …, 2024 - frontiersin.org
Osteoporosis is a systemic metabolic disease characterized by disrupted bone
formation/resorption and homeostasis. Flavonoids extracted from traditional Chinese …

Exploring the anti-osteoporosis potential of Petroselinum crispum (Mill.) Fuss extract employing experimentally ovariectomized rat model and network pharmacology …

NM Saeed, LA Ramadan, WA El-Sabbagh, MA Said… - Fitoterapia, 2024 - Elsevier
One of the most prevalent secondary osteoporosis is ovariectomy-induced osteoporosis.
Parsley (Petroselinum crispum) has potent estrogenic and antioxidant properties and was …

Luteolin-loaded biocomposites containing tantalum and polyimide with antibacterial effects for facilitating osteogenic differentiation and bone bonding

Z Wu, R Kaewmanee, Q Yang, Z Wang, E Xie… - Journal of Materials …, 2023 - pubs.rsc.org
Polymer-based composites are considered promising candidates for bone repair as they
possess some outstanding advantages over ceramic/metallic/polymeric biomaterials …

[HTML][HTML] Luteolin rescues postmenopausal osteoporosis elicited by OVX through alleviating osteoblast pyroptosis via activating PI3K-AKT signaling

S Chai, Y Yang, L Wei, Y Cao, J Ma, X Zheng, J Teng… - Phytomedicine, 2024 - Elsevier
Background Recently, osteoblast pyroptosis has been proposed as a potential pathogenic
mechanism underlying osteoporosis, although this remains to be confirmed. Luteolin (Lut), a …

Using broadly targeted plant metabolomics technology combined with network pharmacology to explore the mechanism of action of the Yishen Gushu formula in the …

H Liu, C Zhang, Y Chai, Y Zhou, H Zeng… - Journal of …, 2024 - Elsevier
ABSTRACT Ethnopharmacological relevance Yishen Gushu Formula (YSGSF) is composed
of Epimedium, prepared Rehmannia, Drynaria, Eucommia, Dodder, ginseng, Astragalus …

Integrating network pharmacology and experimental validation to explore the mechanisms of luteolin in alleviating fumonisin B1–induced intestinal inflammatory injury

D Wen, W Han, Q Chen, G Qi, M Gao, P Guo, Y Liu… - Toxicon, 2024 - Elsevier
Contamination with fumonisin B1 (FB1) represents a global health problem. FB1 exposure
may also trigger intestinal injury by activating inflammatory responses, leading to a reduction …

[HTML][HTML] Exploring the chemical components of Kuanchang-Shu granule and its protective effects of postoperative ileus in rats by regulating AKT/HSP90AA1/eNOS …

WQ Duan, MC Cai, QQ Ma, P Huang, JH Zhang… - Chinese Medicine, 2024 - Springer
Background Postoperative ileus (POI) is a common obstruction of intestinal content passage
caused by almost all abdominal operations that seriously strokes the quality of life of …

[HTML][HTML] Identification of mitophagy-related biomarkers in human osteoporosis based on a machine learning model

Y Su, G Yu, D Li, Y Lu, C Ren, Y Xu, Y Yang… - Frontiers in …, 2024 - frontiersin.org
Background: Osteoporosis (OP) is a chronic bone metabolic disease and a serious global
public health problem. Several studies have shown that mitophagy plays an important role in …

Multi-omics analysis of kidney, bone and bone marrow explored potential mechanisms of Erzhi Wan against osteoporosis with kidney-Yin deficiency

G Shang, X Zhou, J Yin, X Niu, Y Zhao, X Li… - … of Pharmaceutical and …, 2024 - Elsevier
Osteoporosis (OP) is a metabolic bone disease that can lead to major health challenges.
The theory of Traditional Chinese medicine believes that kidney-Yin deficiency (KYD) is the …