The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
Convergent evolution in SARS-CoV-2 spike creates a variant soup from which new COVID-19 waves emerge
The first 2 years of the COVID-19 pandemic were mainly characterized by recurrent
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …
COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic review and meta-analysis
JW Senefeld, M Franchini, C Mengoli… - JAMA Network …, 2023 - jamanetwork.com
Importance Patients who are immunocompromised have increased risk for morbidity and
mortality associated with coronavirus disease 2019 (COVID-19) because they less …
mortality associated with coronavirus disease 2019 (COVID-19) because they less …
Analysis of anti-SARS-CoV-2 Omicron-neutralizing antibody titers in different vaccinated and unvaccinated convalescent plasma sources
The latest SARS-CoV-2 variant of concern Omicron, with its immune escape from
therapeutic anti-Spike monoclonal antibodies and WA-1 vaccine-elicited sera, demonstrates …
therapeutic anti-Spike monoclonal antibodies and WA-1 vaccine-elicited sera, demonstrates …
A delicate balance between antibody evasion and ACE2 affinity for Omicron BA. 2.75
Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused
successive global waves of infection. These variants, with multiple mutations in the spike …
successive global waves of infection. These variants, with multiple mutations in the spike …
Omicron sublineage BQ. 1.1 resistance to monoclonal antibodies
P Arora, A Kempf, I Nehlmeier, SR Schulz… - The Lancet Infectious …, 2023 - thelancet.com
Vaccination represents the key strategy to control the COVID-19 pandemic through induction
of neutralising antibody responses and T cellassociated immunitythat substantially decrease …
of neutralising antibody responses and T cellassociated immunitythat substantially decrease …
Dengue: update on clinically relevant therapeutic strategies and vaccines
M Palanichamy Kala, AL St. John… - Current Treatment Options …, 2023 - Springer
Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …
significant burden on human health. There are four antigenically distinct serotypes of DENV …
Decline of RSV-specific antibodies during the COVID-19 pandemic
1 Thompson MG, Yoon SK, Naleway AL, et al. Association of mRNA vaccination with clinical
and virologic features of COVID-19 among US essential and frontline workers. JAMA 2022; …
and virologic features of COVID-19 among US essential and frontline workers. JAMA 2022; …
The Omicron variant of concern: Diversification and convergent evolution in spike protein, and escape from anti-Spike monoclonal antibodies
Abstract WHO-defined SARS-CoV-2 variants of concern (VOC) drive therapeutics and
vaccine development. The Omicron VOC is dominating the arena since November 2021, but …
vaccine development. The Omicron VOC is dominating the arena since November 2021, but …
A critical analysis of the use of cilgavimab plus tixagevimab monoclonal antibody cocktail (Evusheld™) for COVID-19 prophylaxis and treatment
D Focosi, A Casadevall - Viruses, 2022 - mdpi.com
Evusheld®(tixagevimab+ cilgavimab; AZD7442) was the first anti-Spike monoclonal
antibody (mAb) cocktail designed not only for treatment but also with pre-exposure …
antibody (mAb) cocktail designed not only for treatment but also with pre-exposure …