SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Biodistribution of extracellular vesicles following administration into animals: A systematic review

M Kang, V Jordan, C Blenkiron… - Journal of extracellular …, 2021 - Wiley Online Library
In recent years, attention has turned to examining the biodistribution of EVs in recipient
animals to bridge between knowledge of EV function in vitro and in vivo. We undertook a …

Microglia in the neuroinflammatory pathogenesis of Alzheimer's disease and related therapeutic targets

Y Cai, J Liu, B Wang, M Sun, H Yang - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide,
characterized by progressive neuron degeneration or loss due to excessive accumulation of …

Microglia in neurodegeneration

S Hickman, S Izzy, P Sen, L Morsett, J El Khoury - Nature neuroscience, 2018 - nature.com
The neuroimmune system is involved in development, normal functioning, aging, and injury
of the central nervous system. Microglia, first described a century ago, are the main …

[PDF][PDF] Damage-associated molecular patterns in inflammatory diseases

JS Roh, DH Sohn - Immune network, 2018 - synapse.koreamed.org
Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that
are released from damaged or dying cells and activate the innate immune system by …

Neuroimmunology of traumatic brain injury: time for a paradigm shift

YN Jassam, S Izzy, M Whalen, DB McGavern… - Neuron, 2017 - cell.com
Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …

Lipid nanoparticle technology for therapeutic gene regulation in the liver

D Witzigmann, JA Kulkarni, J Leung, S Chen… - Advanced drug delivery …, 2020 - Elsevier
Hereditary genetic disorders, cancer, and infectious diseases of the liver affect millions of
people around the globe and are a major public health burden. Most contemporary …

Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Scavenger receptors in host defense: from functional aspects to mode of action

Q Taban, PT Mumtaz, KZ Masoodi, E Haq… - Cell Communication and …, 2022 - Springer
Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous
and encompass the miscellaneous group of transmembrane proteins and soluble secretory …

The origin, fate, and contribution of macrophages to spinal cord injury pathology

LM Milich, CB Ryan, JK Lee - Acta neuropathologica, 2019 - Springer
Virtually all phases of spinal cord injury pathogenesis, including inflammation, cell
proliferation and differentiation, as well as tissue remodeling, are mediated in part by …