Immunoglobulin superfamily adhesion molecules are among the most abundant proteins in
vertebrate and invertebrate nervous systems. Prominent family members are the neural cell …

Abstract PAKs, p21-activated kinases, play central roles and act as converging junctions for
discrete signals elicited on the cell surface and for a number of intracellular signaling …

Actin is a versatile and ubiquitous cytoskeletal protein that plays a major role in both the
establishment and the maintenance of neuronal polarity. For a long time, the most prominent …

The serine/threonine p21-activated kinases (PAKs), as main effectors of the Rho GTPases
Cdc42 and Rac, represent a group of important molecular switches linking the complex …

Alzheimer's disease (AD) is characterized by synapse loss due to mechanisms that remain
poorly understood. We show that the neural cell adhesion molecule 2 (NCAM2) is enriched …

Magnetic nanoparticles are promising new tools for therapeutic applications, such as
magnetic nanoparticle hyperthermia therapy and targeted drug delivery. Recent in vitro …

Cell adhesion molecules of the immunoglobulin superfamily (IgSF) including the neural cell
adhesion molecule (NCAM) and members of the L1 family of neuronal cell adhesion …

The formation of nerve bundles, which is partially regulated by neural cell adhesion
molecule 1 (NCAM1), is important for neural network organization during peripheral nerve …

Although studies have shown that basic fibroblast growth factor (bFGF) can activate
autophagy and promote peripheral nerve repair, the role and the molecular mechanism of …

The actin cytoskeleton is crucial for oligodendrocyte differentiation and myelination. Here we
show that p21-activated kinase 1 (PAK1), a well-known actin regulator, promotes …