Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …

This systematic review and meta-analysis aim to provide the best evidence on the
association between metabolic syndrome (MetS) and uric acid (UA) by determining the size …

Xanthine oxidoreductase (XOR), which is widely distributed from humans to bacteria, has a
key role in purine catabolism, catalyzing two steps of sequential hydroxylation from …

Mammalian xanthine oxidoreductase can exist in both dehydrogenase and oxidase forms.
Conversion between the two is implicated in such diverse processes as lactation, anti …

Increasing evidence suggests that uric acid (UA) is a relevant risk factor for arteriolosclerosis
and recent studies have demonstrated the positive relationship between UA concentrations …

Vitamin D deficiency, a major public-health worldwide, is associated with hyperuricemia but
casual association is questioned. The study was conducted to determine potential causal …

Mangiferin, a natural glucosyl xanthone, was confirmed to be an effective uric acid (UA)-
lowering agent with dual action of inhibiting production and promoting excretion of UA. In …

Background Uric acid (UA) is the end product of purine metabolism, which is thought to be
related to many human diseases, such as nephrolithiasis, gout, cardiovascular disease …

Across the multiple fields of medicine there is increasing interest in preventive approaches
to disease. To help guide preventive approaches to disease, in the 1960s, the World Health …

Background and aims Recently, studies have shown a positive association between serum
uric acid (UA) and metabolic syndrome (MS). To evaluate the predictive capacity and the …